经颅直流电刺激对脑卒中后视觉空间忽略不同参考框架成分的影响

Effects of Transcranial Direct Current Stimulation on Different Referential Framework Components of Visuo-spatial Neglect after Stroke

目的:探究右后顶叶皮层经颅直流电刺激对脑卒中后视觉空间忽略患者以自身为中心参考框架成分和非自身为中心参考框架成分的影响。方法:20名右侧半球脑卒中后左侧视觉空间忽略患者随机分为观察组和对照组各10例,观察组行经颅直流电刺激联合常规康复治疗,对照组只进行常规康复治疗。治疗前和治疗2周后对2组患者进行自身为中心成分(线段二等分)、非自身为中心成分(缺口探查)行为学评估。结果:治疗2周后,观察组线段二等分偏侧化评分和左侧缺口圆标记错误评分治疗前后差值和治疗后与对照组差值比较差异均有统计学意义(均P<0.05),但对照组以上评分治疗前后差值比较均无统计学意义。结论:右后顶叶皮层经颅直流电刺激对视觉空间忽略患者不同参考框架下成分均有促进恢复作用。

Objective:To explore the effects of right parietal transcranial direct stimulation(tDCS)on the components in different referential framework of visuo-spatial neglect.Methods:A total of 20 visuo-spatial neglect patients were randomly divided into treatment group(n=10)and control group(n=10).Ten patients in treatment group received tDCS and conventional physical therapeutic interventions,and 10 patients in control group only received conventional physical therapeutic interventions.Both groups received behavioral cognitive tests before and after treatment for 2 weeks,including egocentric reference framework component(line bisection test)and allocentric reference framework component(gap detection test).Results:Two weeks after treatment,there were significant differences in the lateralized score of line bisection task and the score of wrong marked circle with left gap in treatment group before and after treatment,and between treatment group and control after treatment(all P<0.05),but there was no significant difference in control group before and after treatment.Conclusions:The anodal tDCS on the right posterior parietal cortex facilitated the improvement of behavioral performance of both egocentric and allocentric reference framework components in right hemispheric stroke patients with visuo-spatial neglect.