金属有机框架色谱固定相的研究进展

Progress in Metal-Organic Frameworks as Stationary Phase for Chromatographic Separation

金属有机框架(MOFs)是由金属离子或金属簇与有机配体通过配位作用自组装形成的一类新型多孔材料.MOFs具有独特的拓扑结构、丰富的孔隙结构、可调的孔道尺寸、巨大的比表面积以及灵活的表面修饰等特征,是色谱分离领域颇受关注的一类新型固定相.综述了近几年MOFs材料作为固定相在气相色谱、液相色谱及手性拆分等领域应用的研究进展,展现MOFs材料在色谱分离领域的优异性能和应用潜力,并对MOFs材料在色谱固定相领域今后的发展进行了展望.

Metal-organic frameworks(MOFs)are a new class of porous materials which are self-assembly through coordination interactions between metal ions or metal clusters and organic ligands.The characteristics of MOFs,including unique topological structure,porous structure,tunable pore size,high specific surface area,and flexible surface functionalities,enable MOFs to be a new kind of stationary phase materials in the chromatographic field.The progress of MOFs used as stationary phases in gas chromatography(GC),liquid chromatography(LC)and chiral separation in recent years is summarized.The outstanding separation performances and applications of MOFs in the chromatographic separation field are demonstrated.The prospect of MOFs for the chromatographic stationary phase is described.