卷烟主流烟气中相关成分含量的快速检测方法

Rapid Detection of Relevant Components in Mainstream Cigarette Smoke

建立了一种快速测定卷烟主流烟气中相关成分的方法,其中包括一氧化碳、4-(甲基亚硝氨基)-3-吡啶-1-丁酮(NNK)、苯酚、巴豆醛、氨和氰化氢6种相关成分.采用在吸烟机上同时使用溶剂捕集和滤片捕集的方式,溶剂捕集氨、氰化氢和巴豆醛,滤片捕集NNK、氨、氰化氢和苯酚,样品采集后分别在高效液相色谱、离子色谱和液相色谱/质谱联用仪上检测.一氧化碳使用吸烟机自带的非散射红外检测器检测.试验结果表明,与检测卷烟烟气中6种相关成分的烟草行业标准方法相比,简化了分析程序,避免重复抽吸卷烟的捕集步骤,得到的NNK相对标准偏差(RSD)小于6.0%,其它检测结果的RSD均小于3.0%,方法精密度良好,适合卷烟主流烟气中相关成分含量的测定.

A rapid method for the determination of related components in mainstream cigarette smoke,including carbon monoxide,4-(methylnitrosamine)-3-pyridine-1-butanone(NNK),phenol,crotonaldehyde,ammonia and hydrogen cyanide,was set up.Solvent trapping and filter trapping methods were used to trap on the smoking machine at the same time.Ammonia,hydrogen cyanide and crotonaldehyde were trapped by the solvent trapping method,and NNK,ammonia,hydrogen cyanide and phenol were trapped by the filter trapping method.Then the samples were detected using high-performance liquid chromatography(HPLC),ion chromatography(IC)and liquid chromatography/mass spectrometry(LC/MS).Carbon monoxide was detected on the non scattering infrared detector of the smoking machine.The test results showed that comparing with the tobacco industry standard method for the detection of 6 related components in cigarette smoke,the relative standard deviation(RSD)of NNK was less than 6.0%,and RSD of other detection results were less than 3.0%,which is suitable for the determination of the content of related components in mainstream cigarette smoke.