腹腔镜与开腹手术治疗直肠癌的效果及预后分析

Effect and Prognosis of Rectal Cancer Treated with Laparoscopic Surgery,and with Laparotomy Surgery:Comparison and Analysis

为探讨腹腔镜与开腹手术治疗直肠癌的效果及预后,选取本院收治的82例直肠癌患者,随机分为观察组和对照组,各41例。观察组采用腔镜直肠癌根治术治疗,对照组采用传统开腹直肠癌根治术治疗,比较两组手术切口长度、出血量、手术时间、术后排气时间,胃泌素与胃动素含量,血清指标及并发症发生情况。结果显示,与对照组比较,观察组切口更小,出血量更少,手术时间和术后排气时间更短,胃泌素和胃动素含量更高(P<0.05)。观察组C反应蛋白、肿瘤坏死因子-α与白介素-6水平及并发症发生率均低于对照组(P<0.05)。结果表明,与传统手术比较,腹腔镜直肠癌根治术疗效更佳,可减少出血量,对血清指标有显著改善作用,且术后并发症发生率更低,具有临床推广价值。

This study was to investigate the effect and prognosis of rectal cancer treated with laparoscopic surgery,and with laparotomy surgery,randomly divided 82 rectal cancer patients treated in author’s hospital into observation group(41 cases,received laparoscopic radical surgery)and control group(41 cases,routine laparotomy radical surgery);then,compared both groups’length of operative incision,bleeding volume,opeating time,postoperative flatus time,the levels of motilin and gastrin,serum norms,and complication status.As results,compared with control group,the incision,bleeding volume,time for operating and postoperative flatus,as well as levels of motilin and gastrin observation group was more smaller,more less,mor shorter,as well as more higher(P<0.05);in the levels of CRP,TNF-αand IL-6,and in complication incidence observation group was all lower than control group(P<0.05).Resuls show that laparoscopic surgery has more better effect than routine laparotomy surgery,and,can reduce bleeding volume,significantly improve serum norms,its postoperative complication incidence is also more lower,thus has clinical value to be popularized.