益气活血法联合常规西药治疗陈旧性心肌梗死气虚血瘀证45例

Clinical effect of Qi-tonifying and blood-activating therapy combined with conventional Western medicine treatment in treatment of patients with old myocardial infarction with Qi deficiency and blood stasis syndrome: An analysis of 45 cases

目的:观察益气活血法联合常规西药治疗陈旧性心肌梗死气虚血瘀证患者的疗效。方法:将90例陈旧性心肌梗死气虚血瘀证患者随机分为治疗组与对照组,每组各45例。对照组采用常规西药治疗,治疗组在对照组基础上配合益气活血法治疗。观察2组中医证候疗效及左室舒张末期内径(LVEDD)、左室收缩末期内径(LVESD)、左室射血分数(LVEF)、心排血量(CO)等心功能指标。结果:总有效率治疗组为93.3%(42/45),对照组为73.3%(33/45),2组比较,差异有统计学意义(P<0.05)。治疗后,治疗组LVEDD、LVESD明显低于对照组,LVEF、CO明显高于对照组,差异均有统计学意义(P<0.01)。结论:采用益气活血法联合常规西药治疗陈旧性心肌梗死气虚血瘀证可有效提升治疗效果,改善患者心功能,促进疾病康复。

Objective: To investigate the clinical effect of Qi-tonifying and blood-activating therapy combined with conventional Western medicine treatment in the treatment of patients with old myocardial infarction with Qi deficiency and blood stasis syndrome.Methods: A total of 90 patients with old myocardial infarction with Qi deficiency and blood stasis syndrome were randomly divided into treatment group and control group, with 45 patients in each group.The patients in the control group were given conventional Western medicine treatment, and those in the treatment group were given Qi-tonifying and blood-activating therapy in addition to the treatment in the control group.The two groups were compared in terms of outcome of traditional Chinese medicine(TCM) syndrome and cardiac function parameters including left ventricular end-diastolic diameter(LVEDD),left ventricular end-systolic diameter(LVESD),left ventricular ejection fraction(LVEF),and cardiac output(CO).Results: There was a significant difference in overall response rate between the treatment group and the control group [93.3%(42/45)vs73.3%(33/45),P<0.05].Compared with the control group after treatment, the treatment group had significantly lower LVEDDand LVESD and significantly higher LVEF and CO(P<0.01).Conclusion: In the treatment of old myocardial infarction with Qi deficiency and blood stasis syndrome, Qi-tonifying and blood-activating therapy combined with conventional Western medicine treatment can effectively improve treatment outcome and cardiac function and promote disease recovery.