子宫内膜容受性影响因素的研究进展

Research advances in affecting factors of endometrial receptivity

妊娠的建立主要取决于胚胎的质量与子宫内膜容受性,而在现今获取高质量胚胎技术较为成熟的情况下,不孕症患者在多次移植周期后仍无法成功妊娠的原因可能是子宫内膜容受性存在缺陷。子宫内膜容受性是子宫内膜允许胚胎着床的特定状态。任何影响内膜容受性的因素都可能阻碍胚胎的着床,降低妊娠率。本文将从解剖学、细胞学和分子生物学等方面对子宫内膜容受性的影响因素进行综述。

The establishment of pregnancy mainly depends on the quality of embryo and endometrial receptivity.However,in the current situation that the technology of obtaining high-quality embryos is relatively mature,the reason why infertile patients still fail to get pregnant after multiple transplantation cycles may be the defect of endometrial receptivity.Endometrial receptivity is the specific condition of the endometrium that allows the embryo to be implanted.Any factors affecting endometrial receptivity may hinder embryo implantation and reduce pregnancy rate.This article will review the factors affecting endometrial receptivity from the aspects of anatomy,cytology and molecular biology.