呼气峰值流量在儿童哮喘诊断及管理中的应用进展

Role of peak expiratory flow in the assessment and management of asthma in children

呼气峰值流量(peak expiratory flow,PEF)是一种简单、可靠、低成本的肺功能检查方法。PEF可反映呼气气流受限情况,其变异率可判断气流受限有无可逆性,为儿童哮喘的诊断提供客观依据。短期监测PEF可协助管理哮喘急性发作、查找诱发因素、评估治疗效果等。长期监测PEF有助于哮喘控制的评估及预警急性发作,适用于重度哮喘患儿。该文就儿童PEF的检查方法、影响因素、结果判读,以及在儿童哮喘诊断和管理中的应用进展进行综述,为儿童PEF的临床应用提供参考。[中国当代儿科杂志,2021,23 (6):645-649]

Peak expiratory flow(PEF) is a portable, reliable, and inexpensive method for lung function assessment.PEF can reflect expiratory airflow limitation and its variability can document reversibility, which provides an objective basis for the diagnosis of asthma in children. Short-term PEF monitoring can be an important aid in the management of acute asthma exacerbations, identification of possible triggers, and assessment of response to treatment. Long-term PEF monitoring can assist in the assessment of asthma control and warning of acute exacerbations, and this is useful for children with severe asthma. This article reviews the measurements, influencing factors, interpretation, and application of PEF, and its role in the diagnosis and management of asthma in children, to provide references for the clinical application of PEF in children. [Chinese Journal of Contemporary Pediatrics, 2021, 23(6): 645-649]