期刊文献+

术中持续静脉输注利多卡因的应用进展 被引量:2

Progress in the application of intraoperative continuous intravenous infusion of lidocaine
下载PDF
导出
摘要 利多卡因属于酰胺类局麻药,其主要通过可逆性阻断神经细胞膜上Na+通道,阻断伤害性刺激向中枢神经系传导,发挥局部麻醉作用。同时,利多卡因为IB类抗心律失常药物,其主要通过轻度阻断心肌细胞Na+通道而发挥作用,常用于室性心律失常的治疗。目前,随着对利多卡因研究的深入,其除了具有经典的局麻及抗室性心律失常作用,同时还具有术后镇痛、器官保护及抗炎等作用。
作者 唐慧洁(综述) 李玉和(审校) TANG Huijie;LI Yuhe
出处 《云南医药》 2021年第3期275-277,共3页 Medicine and Pharmacy of Yunnan
  • 相关文献

参考文献8

二级参考文献61

  • 1Wei M.Kuukasjarvi P.Laurikka J.et al.Cytokine responses and myocardial injury in coronary artery bypass grafting.Scand J Clin Lab Invest,2001,61:161-166.
  • 2Lahav M,Levite M,Bassani L,et al.Lidocaine inhibits secretion of IL-8 and IL-1beta and stimulates secretion of IL-1 receptor antagonist by epithelial cells.Clin Exp Immunol,2002,127:226-233.
  • 3Taniguchi T,Shibata K,Yamamoto K,et al.Effects of lidocaine administration on hemodynamics and cytokine responses to endotoxemia in rabbits.Crit Care Med,2000,28:755-759.
  • 4Nishina K,Mikawa K,Sbiga M,et al.Attenuation of hyperoxia-induced diaphragmatic dysfunction with lidocaine in hamsters.Crit Care Med,2000,28:1973-1978.
  • 5Campistol JM, Sacks SH. Mectmnisms of nephrotoxicity. Transplantation, 2000,69 : SS5-10.
  • 6Dennis MJ, Foster MC, Ryan J J, et al. The increasing importance of chronic rejection as a cause of renal allograft failure. Transpl Int,1989,2:214-217.
  • 7Beloeil H, Mazoit JX. Effect of local anesthetics on the post operative inflammatory response. Ann Fr Anesth P, eanim, 2009,28:231-237.
  • 8Lauretti GR. Mechanisms of analgesia of intravenous lidocaine. Rev Bras Anestesiol, 2008 , 58. 280- 286.
  • 9Hollmann MW, Strumper D, Herroeder S, et al. Receptors, G proteins, and their interactions. Anesthesiology, 2005, 103:1066-1078.
  • 10Hara K, Sata T. The effects of the local anesthetics lidocaine and procaine on glycine and garnma-aminobutyric acid receptors expressed in Xenopus Ooeytes. Anesth Analg, 2007, 104:1434-1439.

共引文献68

同被引文献42

引证文献2

二级引证文献13

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部