越南、马来西亚、菲律宾2007-2019年主要呼吸道病毒传染病流行现状系统评价

A systematic review of prevalent epidemics of major respiratory viral infectious diseases in Vietnam,Malaysia and Philippine,2007-2019

目的了解越南、马来西亚、菲律宾等我国南海周边邻国呼吸道病毒传染病的流行现状。方法通过检索PubMed、Web of science、EmBase、Medline、Scopus、Google scholar等数据库2015年1月至2020年6月发表的越南、马来西亚、菲律宾3国的呼吸道病毒传染病相关文献,对文献进行筛选和总结,分析主要呼吸道病毒传染病的病毒类型、检测阳性率、人群分布、季节性和地区分布等。结果共38篇文献被纳入本系统综述,研究时间为2007-2019年。越南主要的呼吸道病毒为流感病毒(IFV,3.0%40.6%)、呼吸道合胞病毒(RSV,6.2%48%)和鼻病毒(HRV,8.8%42.0%);马来西亚的主要呼吸道病毒为IFV(3%40.6%)和RSV(16.7%51.0%);菲律宾也为IFV(6.0%17.0%)和RSV(7.2%31.6%)。IFV表现出雨季旱季的两个季节性,且甲型流感(IAV)多于乙型流感(IBV);上述3国RSV感染均多发于婴儿,越南和马来西亚RSV感染表现为雨季多见。此外,腺病毒(ADV)、副流感病毒(PIV)、人博卡病毒(HBoV)、冠状病毒(HCoV)、人偏肺病毒(HMPV)等也有报道。结论 IFV、RSV和HRV是2015-2020年越南、马来西亚、菲律宾3个我国南海周边主要邻国流行的主要呼吸道病毒传染病,提示我国南海周边省份应进一步加强相关疾病监测和预防。

Objective To evaluate the prevalent epidemics of major respiratory viral infectious diseases in neighboring countries of the South China Sea such as Vietnam,Malaysia and Philippines from 2007 to 2019.Methods We performed a systematic literature search for articles on respiratory viral infectious diseases from PubMed,Web of Science,Embase,Medline,Scopus and Google scholar published from January 2015 to June 2020.Studies reporting data on the prevalence and the epidemic situation of respiratory viral infectious diseases were selected for analysis.Methodological quality of the studies was as-sessed using AHRQ(The Agency for Healthcare Research and Quality)and NOS(The Newcastle-Ottawa Scale)criteria.Results A total of 38 observational studies were identified following the inclusion criteria,from 2007 to 2019.The major respiratory viruses in Vietnam were influenza virus(IFV,3.0%-40.6%),respiratory syncytial virus(RSV,6.2%-48%)and rhinovirus(HRV,8.8%-42.0%);Malaysia's primary respiratory viruses were IFV(3.0%~40.6%)and RSV(16.7%-51%);the main respiratory viruses of Philippines were IFV(6.0%-17.0%)and RSV(7.2%-31.6%).The prevalence of IFV typically rose in both rainy season and dry season,and the number of influenza A(IAV)cases was more than influenza В (IBV).Moreover,RSV infec-tion mostly occurred in infants in these three countries,and was more common in the rainy season particularly in Vietnam and Malaysia.In addition,adenovirus(ADV),parainfluenza virus(PIV),human Boca virus(HBoV),coronavirus(HCoV),human metapneumovirus(HMPV),etc.have also been reported in the past five years.Conclusions Respiratory infectious viruses es-pecially IFV,RSV and HRV are common in major neighboring countries of the South China Sea such as Vietnam,Malaysia and Philippines,underscoring the importance of enhancing surveillance and prevention of related diseases in neighboring provinces of China.