基于Web of Science和CNKI甲状腺癌文献循证可视化及对比分析

Evidence-based visualization and comparative analysis of literature on thyroid cancer based on Web of Science and CNKI

目的运用文献计量学的方法分析中、英文数据库中甲状腺癌的研究现状,探索其当前研究热点和未来研究方向。方法分别采用Web of Science和中国知网(CNKI)数据库进行中、英文文献的检索。以“甲状腺癌”为检索词,检索日期自建库至2021-03-20,纳入已发表甲状腺癌的相关文献,采用VOSviewer 1.6.11软件对纳入文献的国家、机构及作者等分布、关键词的聚类及其时序分析,绘制对应的循证可视化图谱。结果分别纳入10721篇和27485篇的中、英文文献。结果显示,中、英文文献的年发文量均逐年递增;英文文献在2005年后年发文量的递增趋势更加显著,而中文文献在2009年前后才出现明显递增;在国家和机构方面,英文文献中发文量较大的国家(Top10),绝大多数为欧美及日韩等发达国家,且欧美国家机构间的合作紧密程度较好;然而,中文文献中的发文机构间的合作网络较为局限,呈现出明显的地域性;关键词聚类方面,英文文献的结果提示未来潜在的研究热点为甲状腺癌的分子机制、BRAF突变、外科手术的规范与标准以及甲状腺癌的超声诊断等,而中文文献的聚类相对分散,其聚类主要可归纳为甲状腺癌的诊断、暴露因素及内科治疗和甲状腺癌手术治疗等,且尚未发现甲状腺癌分子机制研究的聚类。结论甲状腺癌的中文文献研究主题明显滞后于英文文献。虽然当前甲状腺癌的研究热点较为分散,但未来应关注甲状腺癌的基础研究、BRAF突变靶向治疗、甲状腺癌的淋巴结清扫和甲状腺癌新型的诊断方法等研究领域。

Objective To analyze the current research topics of thyroid cancer in Chinese and English databases using the bibliometric,then to explore its current hotspots and future research directions.Methods Web of Science and CNKI were used to search Chinese and English published records,respectively.The word of"thyroid cancer"was used as the search term from the establishment of the database to March 20,2021.Subsequently,the published records related on thyroid cancer were ultimately included.The distribution of countries,institutions,authors,keywords of all identified records were clustered and visualized via VOSviewer 1.6.11 software,to draw the corresponding evidencebased visualization.Results Finally,10721 records in Chinese and 27485 hits in English were identified.The annual publication volume of both Chinese and English documents increasingly gained the number year by year.Particularly,the trend of the annual publication volume of English records was significantly increased after the year of 2005,while the Chinese documents increased significantly until the year of 2009.In terms of countries and institutions,in English documents,most of Top 10 countries were developed countries such as Europe,America,Japan and South Korea.Moreover,the cooperation in European and American countries and institutions was relatively close.However,the cooperation network in Chinese records was relatively limited and obviously regional.It was suggested that the potential research hotspots might include the molecular mechanism of thyroid cancer,BRAF mutations,standards of radical thyroidectomy and the ultrasound diagnosis in future.The clustering results of Chinese records was relatively scattered,which could be mainly defined as diagnosis methods,exposure factors,medical treatment and surgical treatment of thyroid cancer,and the cluster of molecular mechanism research on thyroid cancer was still to be formed.Conclusion The research topics of Chinese literature on thyroid cancer lag significantly behind the English literature.Although the current research hotspots of thyroid cancer are relatively scattered,in the future,attention should be paid to the basic research of thyroid cancer,BRAF mutation targeted therapy,lymph node dissection for thyroid cancer,and new diagnostic methods for thyroid cancer.