老年冠心病患者红细胞分布宽度与运动耐力关系研究

Relationship between red cell distribution width and exercise tolerance in elderly patients with coronary heart disease

目的探讨老年冠心病(CHD)患者红细胞分布宽度(RDW)与运动耐力的相关性。方法纳入北部战区总医院体检65岁以上老年冠心病患者中资料完整者172例,依据6 min步行距离(6MWD)分为3组:Ⅰ组(≥360 m),Ⅱ组(>241 m~<360 m),Ⅲ组(≤240 m),分析RDW与运动耐力的相关性。结果随运动耐力下降,中性粒细胞淋巴细胞比例(NLR)及RDW升高,血清钠下降,差异均有统计学意义(P值均<0.01)。基于多变量logistic回归分析,运动耐力与RDW(r=-0.196)呈显著负相关。结论血液中RDW与老年CHD患者运动耐力相关,可作为评估老年CHD患者活动耐力的重要指标。

Objective To investigate the correlation between red cell distribution width(RDW)and exercise tolerance in elderly patients with coronary heart disease(CHD).Methods 172 patients with CHD(≥65)whose health information was completed were included in the physical examination in the General Hospital of the Northern Theater Command.According to the 6 minute walking distance(6MWD),they were divided into three groups:Ⅰ(≥360 m),Ⅱ(>241 m~<360 m),Ⅲ(≤240 m)to analyze the correlation between RDW and exercise tolerance.Results With the decrease of exercise tolerance,the level of RDW and the neutrophil-to-lymphocyte ratio(NLR)was gradually increased,while the serum sodium(NA)was gradually decreased.The difference was statistically significant(P<0.01).Based on multivariable logistic regression,there was a significant negative correlation between exercise tolerance and RDW(r=-0.196).Conclusion RDW is associated with exercise tolerance in elderly patients with CHD,and can be used as a useful indicator to evaluate exercise tolerance in elderly patients with CHD.