单唾液酸四己糖神经节苷脂钠联合中频电疗治疗小儿脑瘫的疗效探析

Analysis of the Curative Effect of Monosialotetrahexose Ganglioside Sodium Combined with Intermediate Frequency Electrotherapy in the Treatment of Children with Cerebral Palsy

目的分析单唾液酸四己糖神经节苷脂钠联合中频电疗治疗小儿脑瘫的疗效。方法依据该院2017年8月—2020年4月期间小儿脑瘫的收治情况,共对56例患儿进行了分析,按照家属意愿分成两组,分别使用康复治疗(对照组)与单唾液酸四己糖神经节苷脂钠联合中频电疗治疗(观察组),对比两组的GESELL评分、行为异常改善情况和疗效。结果观察组治疗后大运动评分(38.22±5.28)分,精细运动评分(42.79±7.28)分,适应性评分(58.38±6.26)分,语言评分(48.86±9.25)分,个人社交评分(42.43±3.27)分,数据高于对照组,差异有统计学意义(t=5.413、2.385、5.527、3.218、5.046,P<0.05);观察组意识障碍改善时间(3.44±0.47)d,肌张力异常改变时间(6.85±1.33)d,原始反射异常改变时间(7.04±1.74)d,数据比对照组低,差异有统计学意义(t=5.960、11.032、5.756,P<0.05);观察组与对照组治疗有效率分别是89.29%(25例)、53.57%(15例),观察组更高,差异有统计学意义(χ2=6.269,P<0.05)。结论单唾液酸四己糖神经节苷脂钠联合中频电疗治疗小儿脑瘫疗效显著,可以有效提升患儿发育质量,促进神经异常行为的改善。

Objective To analyze the efficacy of monosialotetrahexose ganglioside sodium combined with intermediate frequency electrotherapy in the treatment of children with cerebral palsy.Methods Based on the admission and treatment of children with cerebral palsy from August 2017 to April 2020 in the hospital,a total of 56 children with cerebral palsy were analyzed,and they were divided into two groups according to the wishes of their families,using rehabilitation therapy(control group)and monosialic acid IV.Hexoseganglioside sodium combined with intermediate frequency electrotherapy(observation group),the GESELL score,improvement of behavioral abnormalities and curative effect of the two groups were compared.Results After treatment,the observation group had a major motor score(38.22±5.28)points,a fine motor score(42.79±7.28)points,an adaptability score(58.38±6.26)points,a language score(48.86±9.25)points,and a personal social score(42.43±3.27)points,higher than the control group,and the difference was statistically significant(t=5.413,2.385,5.527,3.218,5.046,P<0.05);the improvement time of consciousness disorder in the observation group(3.44±0.47)d,the time of abnormal muscle tone change(6.85±1.33)d,the original reflex abnormal change time(7.04±1.74)d,the data was lower than the control group,and the difference was statistically significant(t=5.960,11.032,5.756,P<0.05);the observation group and the control group had treatment effective rates of 89.29%(25 cases)and 53.57%,respectively(15 cases),the observation group was higher,and the difference was statistically significant(χ2=6.269,P<0.05).Conclusion The monosialotetrahexose ganglioside sodium combined with intermediate frequency electrotherapy has a significant effect in the treatment of children with cerebral palsy,which can effectively improve the development quality of children and promote the improvement of abnormal neurological behaviors.