聚桂醇注射治疗静脉畸形及其美学效果评价

Injection treatment of venous malformation by lauromacrogol and aesthetic effect evaluation

目的探讨病灶内注射聚桂醇治疗静脉畸形的近期效果及远期美学效果。方法回顾性分析自2015年8月至2019年12月,中国人民解放军空军军医大学第一附属医院整形外科采用聚桂醇治疗68例静脉畸形患者的临床资料,对聚桂醇治疗静脉畸形的有效率及远期美学效果进行评价。结果聚桂醇注射治疗静脉畸形有效率86.8%,远期美学评分≥4分者占69.1%。对于不同年龄段和病灶位于不同部位的患者近期效果,及远期美学效果比较差异无统计学意义(P>0.05)。聚桂醇治疗单发病灶的近期效果和远期美学效果明显优于多发病灶(P<0.05)。当病灶直径≤3 cm时,聚桂醇显示出更好的近期治疗效果和远期美学效果,相比于病灶>3 cm,其差异有统计学意义(P<0.05)。结论注射聚桂醇治疗静脉畸形是一种安全、有效的方法,其具有用量较小、疗效较显著、不良反应较少及美学效果良好的优点,并在小病灶、单发病灶治疗中更有优势,值得临床推广使用。

Objective To explore the short-term curative effect and long-term aesthetic effect of intralesional injection of lauromacrogol in the treatment of venous malformation.Methods The clinical data of 68 patients with venous malformation admitted in The First Affiliated Hospital of Air Force Medical University of PLA from August 2015 to December 2019 were retrospectively analyzed,to evaluate the effective rate and long-term aesthetic effect of cinnamyl alcohol in the treatment of venous malformations.Results The effective rate of lauromacrogol injection in the treatment of venous malformation was 86.8%,and the long-term aesthetic scores≥4 was 69.1%.There was no significant difference in the short-term curative effect and long-term aesthetic effect of patients with different ages and different parts(P>0.05).The short-term curative effect and long-term aesthetic effect of lauromacrogol in the treatment of single lesion were significantly better than the treatment of multiple lesions(P<0.05).When the lesion diameter was less than or equal to 3 cm,lauromacrogol showed good short-term curative effect and long-term aesthetic effect.Compared with the lesion diameter more than 3 cm,the difference was statistically significant(P<0.05).Conclusion Lauromacrogol injection is a safe and effective method in the treatment of venous malformation.It has the advantages of less dosage,significant curative effect,less adverse reactions and good anesthetic effect.It has more advantages in the treatment of small lesions and single lesions.It should be considerable for clinical application.