桂枝附子汤治疗神经根型颈椎病(太阳病阳虚表证)的临床研究

Clinical Study of Guizhi Fuzi Decoction in the Treatment of Cervical Spondylotic Radiculopathy(Taiyang Disease Syndrome with Surface Yang Deficiency)

目的:观察桂枝附子汤治疗神经根型颈椎病(太阳病阳虚表证)的临床疗效。方法:按随机对照设计,将符合纳入标准的60例患者均分为治疗组和对照组,治疗组服用桂枝附子汤,对照组服用塞来昔布胶囊联合甲钴胺片,以临床疗效、疼痛视觉模拟评分(VAS)、症状和体征(颈椎疼痛、肢体麻木、颈项活动)评分及颈椎功能障碍指数(NDI),分别在治疗前、治疗后2周、治疗后3个月末次随访进行评定。结果:治疗组有效率为90.00%,对照组有效率为86.67%,差异有统计学意义(P<0.05);两组在VAS评分、症状和体征评分、NDI评分与治疗前比较均有改善,并且治疗组优于对照组,差异均有统计学意义(P<0.05)。结论:桂枝附子汤对神经根型颈椎病(太阳病阳虚表证)疗效显著,可以改善神经根型颈椎病在颈、项、肩、上肢等部位出现的僵硬、活动受限、怕冷、困重、乏力、疼痛、麻木等症状,安全有效,值得推广应用。

Objective:To observe the clinical efficacy of Guizhi Fuzi decoction in the treatment of cervical spondylotic radiculopathy(Taiyang disease syndrome with surface Yang deficiency).Methods:Sixty patients with cervical spondylotic radiculopathy were randomly divided into treatment group(n=30)and control group(n=30).The treatment group was treated with Guizhi Fuzi decoction.The control group was treated with celecoxib capsule and mecobalamin tablets.The clinical efficacy,pain visual analogue scale(VAS),symptoms and signs(cervical pain,limb numbness,cervical activity)and neck disability index(NDI)cervical dysfunction index were evaluated before treatment,2 weeks and 3 months after treatment.Results:The effective rate was 90.00%in the treatment group and 86.67%in the control group and the difference was statistically significant(P<0.05).The VAS score,symptom and sign score and NDI score of the two groups were improved compared with those before treatment(P<0.05).Index in the treatment group were better than these of the control group,and the difference was statistically significant(P<0.05).Conclusion:Guizhi Fuzi decoction has a significant effect on cervical spondylotic radiculopathy(solar disease with Yang deficiency syndrome).It can improve the symptoms of cervical spondylotic radiculopathy in neck,neck,shoulder and upper limb,such as stiffness,limitation of activity,fear of cold,drowsiness,fatigue,pain,numbness and so on.It is safe and effective and is worth popularizing and applying.