钯催化烯烃杂环化反应制备[60]富勒烯二氢呋喃化合物

Palladium-Catalyzed Synthesis of Dihydrofuran-Fused[60]Fullerene Derivatives via Heteroannulation of Olefins

富勒烯二氢呋喃衍生物在光电、医药等领域具有较好的应用前景,近年来已成为研究热点.以氯化钯为催化剂,三氟甲烷磺酸铜为氧化剂,烯烃衍生物和[60]富勒烯为原料,通过C—H键活化和杂环化反应,合成了一系列单取代和双取代的富勒烯二氢呋喃化合物.利用1H NMR、13C NMR、IR和HRMS等对产物的结构进行了表征.通过设计对照实验,对反应机理进行了研究,提出了可能的反应机理.

With the good application prospects in the fields of optoelectronics and medicine,dihydrofuran-fused[60]fullerene derivatives have become a research hot topic in recent years.A series of monosubstituted and disubstituted dihydrofuran-fused[60]fullerene derivatives were synthesized by C—H bond activation and heterocyclic reaction using palladium chloride as catalyst,copper trifluoromethanesulfonate as oxidant,olefins and[60]fullerene as raw materials.The structures of the products were confirmed by 1H NMR,13C NMR,IR and HRMS.The reaction mechanism was studied by designing controlled experiments,and a possible reaction mechanism was proposed.