摘要
在酒石酸催化作用下,以1,3-二噁烷-4,6-二酮、芳香醛、芳香胺和丙酮为原料,通过四组分反应有效地合成了11种双螺环四氢喹啉双(1,3-二噁烷-4,6-二酮)衍生物.该方法具有产物收率高、适用范围较广、反应温和、操作简单及环境友好等优点,同时对反应机理进行了推测.
Eleven dispirotetrahydroquinoline-bis(1,3-dioxane-4,6-dione)derivatives were synthesized by a four-component reaction of 1,3-dioxane-4,6-dione,aromatic aldehydes,arylamines and acetone in the presence of tartaric acid.This method can provide the advantages of high yields,broader substrate scope,mild conditions,simple operation and environmental friendliness.Additionally,the reaction mechanism was also speculated.
作者
许招会
叶华涛
张文峰
肖强
Xu Zhaohui;Ye Huatao;Zhang Wenfeng;Xiao Qiang(Chemistry and Chemical Engineering Department,Jiangxi Normal University,Nanchang 330022;Department of Orthopedics,Jiangxi Province Peopleʼs Hospital,Nanchang 330006)
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2021年第5期2127-2133,共7页
Chinese Journal of Organic Chemistry
基金
江西省研究生创新基金(No.YC2015-B023)
江西省教育厅科技计划研究项目(Nos.GJJ170170,GJJ180892)
江西师范大学博士科研启动基金(No.JXSDBY2020-B012)资助项目.
