血塞通软胶囊综合评价研究

Comprehensive evaluation of Xuesaitong Soft Capsule

目的以临床常用血塞通软胶囊为例,探索中成药综合评价的内容和方法,为中成药的临床合理使用、中成药价值的研究开发以及药品相关决策提供依据,推动安全有效合理用药。方法基于系统检索文献和药品生产企业提供的研究资料,利用循证医学和药物经济学等基本方法,从药学特性、有效性、安全性、经济性、适宜性、可及性和创新性等方面对血塞通软胶囊进行评价。结果血塞通软胶囊有效成分和在说明书适应证上的药理作用明确,临床疗效肯定,安全性良好,服用依从性好,药品质量有保障。结论通过不同的系统检索文献,结果与已经获多个中西医临床诊疗规范和推荐指南中的指标相一致。总之血塞通软胶囊的临床前与临床使用的证据已形成一定的体系,但同时,在不同临床应用中的药理机制挖掘、临床扩展应用中的有效性和安全性、个体精准用药尚需要更深入进行不同研究。

Objective comprehensive evaluation of Chinese patent medicine to take commonly used Xuesaitong Soft Capsule in clinic for instance.It provides foundation for the clinical rational use of Chinese patent medicine,the traditional Chinese medicine value of research and development,and drug related policies.It also promotes clinical safe,effective and rational drug use.Methods Based on the systematic retrieval of literatures and research materials provided by pharmaceutical manufacturers.Using evidence-based medicine and pharmacoeconomics and other basic methods.From the pharmaceutical characteristics,effectiveness,safety,economy,suitability,accessibility and innovation and other aspects,objective to evaluate Xuesaitong Soft capsule.Results pharmacological action of Xuesaitong Soft Capsule is clear on the effective ingredients and indications in the manual.Clinical effect of Xuesaitong Soft Capsule.The safety of Xuesaitong Soft capsule is good.The compliance of Xuesaitong Soft capsule is good.The quality of Xuesaitong Soft capsule is guaranteed.Conclusion indicators that has obtained many clinical diagnosis and treatment norms and recommended guidelines of traditional Chinese and Western medicine by literature searched through different systems.Xuesaitong Soft Capsule in the evidence of preclinical and clinical use has formed a certain system.But at the same time,further studies are needed on the pharmacological mechanism,effectiveness,safety,and individual precise medication in different clinical application.