民族药双参本草考证及现代研究概述

Research on Ethno-Herb of Triplostegia grandifolra and Summary of Modern Research

双参是我国云南少数民族常用于治疗肾脏疾病的药材,始载于《云南中草药选》。通过查阅历代本草及文献资料,对双参药材基源、名称、药用历史沿革、现代研究等方面进行系统本草考证和整理综述。双参原植物为川续断科双参属双参(Triplostegia glandulifera Wall)和大花双参(Triplostegia grandiflora Gagnep),属于补虚药,主治久病体虚、肾虚腰疼、阳痿、遗精、不孕、久咳、月经不调、倒经等。双参主要成分为环烯醚萜类、三萜类、生物碱、咖啡酸甲酯等,推测其可能有脑靶向、抑制肿瘤、降血糖、降血脂、抗溃疡、调理月经、提高机体免疫力等作用。双参作为民族药,目前的临床应用止步于民间经验,临床应用数据缺乏,后续还需大量的实验验证其功效,以更好地开发和利用双参植物资源。

Triplostegia grandifolra is a kind of herbal medicine often used in the treatment of kidney diseases by Yunnan minorities,which was first published in Yunnan ZhongcaoYao Xuan.By referring to literature on herbs at previous dynasties,this paper systematically researched on and summarized Triplostegia grandifolra from the aspects of its origin,name,medical history,modern research and so on.The original plants of Triplostegia grandifolra are Triplostegia glandulifera Wall and Triplostegia grandiflora Gagnep,it belongs to deficiency-supplementing medicine,and is mainly used to treat deficiency constitution due to lingering diseases,kidney deficiency and lumbar pain,impotence,seminal emission,infertility,chronic cough,menstrual irregularities,and inverted menstruation.Its main components comprise iridoids,triterpenoids,alkaloid,and methyl caffeate,etc.It is speculated that it may have the functions of brain targeting,tumor inhibition,hypoglycemia,hypolipidemia,anti-ulceration,menstruation regulation,and improving body immunity,etc.As an ethno-medicine,the current clinical application of Triplostegia grandifolra is limited to folk experience,and clinical application data is lacking.A large number of experiments are needed to verify its effect in the future,so as to better develop and utilize the plant resources of Triplostegia grandifolra.