润便汤治疗癌症便秘临床研究

Clinical Study on Runbian Tang for Constipation Caused by Cancer

目的:观察润便汤治疗癌症便秘的临床疗效。方法:选出杭州市下城区中医院和杭州师范大学附属医院2017年2月—2019年2月诊治的78例癌症便秘患者,根据不同治疗方案将其分成A组与B组各39例,A组予以酚酞治疗,B组予以润便汤治疗,对比2组的症状积分、临床疗效、便秘改善情况(开始排便时间、大便形态复常时间、1周排便次数)及初次排便不良发生率(用力排便、大便干结、有不尽感、有阻塞感)。结果:2组治疗后症状积分较前下降,B组治疗后的症状积分低于A组(P<0.05)。B组总有效率高于A组(P<0.05)。B组开始排便时间及大便形态复常时间均短于A组,且1周排便次数多于A组(P<0.05)。B组初次排便不良发生率低于A组(P<0.05)。结论:润便汤治疗癌症便秘的疗效理想,可快速消除患者的临床症状,改善便秘情况。

Objective:To observe the clinical effect of Runbian tang for constipation caused by cancer.Methods:A total of 78 cases of patients with constipation caused by cancer, diagnosed and treated in the Hangzhou Xiacheng District Traditional Chinese Medicine Hospital and Affiliated Hospital of Hangzhou Normal University from February 2017 to February2019,were selected and divided into Group A and Group B according to the different treatments,39 cases in each group.Group A was treated with phenolphthalein, and Group B was treated with Runbian tang. The symptom scores, clinical effect,improvement of constipation including the beginning time of defecation,the recovery time of stool morphology and the one-week defecation times as well as the incidence of unfavorable conditions in the first defecation including forced defecation, dry stool, incomplete defecation and sense of obstruction in the two groups were compared. Results: After treatment,the symptom scores in the two groups were decreased when compared with those before treatment,and the score in Group B was lower than that in Group A(P<0.05). The total effective rate in Group B was higher than that in Group A(P<0.05). The beginning time of defecation and the recovery time of stool morphology in Group B were shorter than those in Group A, and the one-week defecation times were more(P<0.05). The incidence of unfavorable conditions in the first defecation in Group B was lower than that in Group A(P<0.05). Conclusion:Runbian tang has ideal curative effect in treating constipation caused by cancer,which can quickly eliminate the clinical symptoms of patients and improve the constipation.