不同产地加工方法对前胡药材品质的影响

Effects of Different Habitat Processing Methods on Quality of Peucedani Radix

目的:明确不同产地加工处理对前胡药材品质的影响。方法:以选育品系为材料,统一栽培,同时采收。将形状和质量相近的新鲜白花前胡根进行水洗、干燥、切片处理,记录干燥时间、折干率和霉腐特征。高效液相色谱法(HPLC)测定干燥药材中白花前胡甲素、白花前胡乙素、白花前胡丙素含量。参考《中华人民共和国药典》(以下简称《中国药典》)2020年版方法,对不同材料的灰分、酸不溶灰分进行测定。结果:水洗处理可以很好地控制酸不溶灰分含量,非水洗药材酸不溶灰分高达3%,比《中国药典》2020年版规定指标高50%左右;40、50、60℃烘干的药材中白花前胡甲素、白花前胡乙素、白花前胡丙素含量无显著差异。40、50、60℃烘干药材时间分别为18、22、56 h,切6 mm厚片再进行60℃烘干的药材中白花前胡甲素、白花前胡乙素、白花前胡丙素含量差异无统计学意义,烘干时间为16 h。结论:前胡产地加工需水洗后马上进行低温烘干,烘干温度应控制在60℃以下;产地趁鲜切片加工,切片厚度宜控制在6 mm以上。

Objective:To study the impacts of the quality of Peucedani Radix with different habitat processing methods.Methods:The materials of breeding lines were used in this research.In this experiment,the plant was cultivated at the same condition and harvested at the same time.Then the root with similar shape and weight were selected for the research.After the fresh root was washed,dried,and sliced,the drying times,drying rate and root-rot characteristics of the fresh root of Peucedanum praerupterum were recorded.Meanwhile,the(±)-praeruptorin A,(±)-praeruptorin B,(+)-praeruptorin C of the dried root was determined by HPLC.At last,the ash and acid-insoluble ash of different materials were also measured according to the 2020 edition of Chinese Pharmacopoeia.Results:The acid-insoluble ash content could meet the standards of the 2020 edition of Chinese Pharmacopoeia after washing during habitat processes.If not be washed,the acid-insoluble ash content of Peucedani Radix could reached to 3%,which about 50%exceeded the standard of the 2020 edition of Chinese pharmacopeia.And then,to prevent root-rot,the fresh root of P.praerupterum should be dried immediately after washed.There was no significate different in the composition of(±)-praeruptorin A,(±)-praeruptorin B,(+)-praeruptorin C after dried by 40,50 and 60℃.And 56,22 and 18 h were consumed for dried progresses respectively,at 40,50 and 60℃heat processing condition.Contrast to directly dried root at 60℃,there was also no significant different in the composition of(±)-praeruptorin A,(±)-praeruptorin B,(+)-praeruptorin C,when the fresh materials were cut into 6 mm slice and dried at 60℃.While,the dried progress of sliced root could only use 16 h,when dried at 60℃.Conclusion:The results showed that the habitat processing methods of the Peucedani Radix should to be washed,and then dried immediately at low temperature.And the drying temperature is needed to be controlled below 60℃.If the habitat freshly sliced was needed,the slice should be thicker than 6 mm.