多模式磁共振成像指导下觉醒型脑卒中再灌注治疗的临床研究

The clinical study of reperfusion therapy in patients with wake-up strokes under the guidance of multimodal magnetic resonance imaging

回顾性分析146例觉醒型脑卒中(WUS)患者,依据头颅磁共振成像(MRI)弥散加权成像(DWI)/液体衰减反转回复(FLAIR)序列或灌注加权成像(PWI)/核心梗死体积不匹配行再灌注治疗。其中62例患者行再灌注治疗后,24 h NIHSS评分及90 d mRS评分分值低于未再灌注治疗的患者(84例),其症状性颅内出血发生率及病死率未增加。多模式MRI指导WUS患者的再灌注治疗是安全有效的治疗方法。

The clinical date of 146 patients with wake-up strokes(WUS)were retrospectively analyzed.Reperfusion therapy in 62 patients with WUS was performed according to the mismatch of cerebral MRI DWI/FLAIR or PWI/Core Infarct Volume.The scores of 24 h NIHSS and 90 d mRS in reperfusion were lower than those of the 84 patients in WUS non-reperfusion.The incidence symptomatic intracranial hemorrhage and mortality did not increase.Reperfusion therapy for WUS patients under the guidance of multimodal magnetic resonance imaging is safe and effective.