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口腔颌面部腺样囊性癌嗜神经侵袭的临床分析

Clinical analysis of oral and maxillofacial region adenoid cystic carcinoma with perineural invasion
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摘要 目的探讨口腔颌面部腺样囊性癌(ACC)嗜神经侵袭(PNI)发生情况及相关影响因素。方法回顾性分析2008年1月至2016年12月山西省肿瘤医院收治的55例口腔颌面部ACC患者的临床资料,采用多元logistic回归模型分析患者临床特征与PNI发生的相关性。结果55例患者中发生PNI 25例(45.5%),其中腮腺7例、腭部2例、口底1例、颌下腺9例、口咽1例、颊黏膜2例、唇2例、舌下腺1例。多因素分析结果显示,性别(95%CI 1.013-16.270,P=0.048)、肿瘤部位(95%CI 1.253-17.019,P=0.022)是影响肿瘤PNI发生的独立危险因素。结论性别、肿瘤部位与ACC患者PNI发生有关,可为临床治疗方案选择提供方向。
作者 李智林 高泽慧 南杰 皇甫辉 朱宝燕 张茜 Li Zhilin;Gao Zehui;Nan Jie;Huangfu Hui;Zhu Baoyan;Zhang Xi(Department of Head and Neck Surgery,Shanxi Provincial Cancer Hospital,Taiyuan 030013,China;Department of Otolaryngology,Head and Neck Surgery,the First Hospital of Shanxi Medical University,Taiyuan 030001,China)
出处 《肿瘤研究与临床》 CAS 2021年第5期373-375,共3页 Cancer Research and Clinic
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