摘要
金黄色葡萄球菌(SA)在全球范围内引起了许多社区获得性及医院获得性感染,生物膜的形成是细菌适应其生存环境的一种生存策略。在生物膜的保护下,生物膜中的细菌对抗生素和免疫应答产生了耐受性和抗性,使得与生物膜相关的感染难以治疗。因此,SA生物膜的防治一直以来是研究的热点。本文概述了消除SA生物膜的形成和相关感染的最新预防和治疗策略。
Staphylococcus aureus(SA)has caused many community-acquired and hospital-acquired infections around the world.The formation of biofilm is a kind of survival strategy for bacteria to adapt to their living environment.Under the protection of biofilm,bacteria in biofilm have become tolerant and resistant to antibiotics and the immune responses,making it difficult to treat infections associated with biofilm.Therefore,the prevention and treatment of SA biofilm has always been a research focus.This review summarizes the latest prevention and treatment strategies to eliminate SA biofilm formation and related infections.
作者
郑杨
查何
ZHENG Yang;ZHA He(Department of Clinical Laboratory,the Third Affiliated Hospital of Zunyi Medical University,Guizhou Province,Zunyi 563000,China)
出处
《中国医药导报》
CAS
2021年第18期32-35,共4页
China Medical Herald
基金
国家自然科学基金地区科学基金项目(81760475)
贵州省遵义市联合科技基金项目[遵市科合HZ字(2019)173号]。
关键词
金黄色葡萄球菌
生物膜
感染
防治
Staphylococcus aureus
Biofilm
Infection
Prevention and treatment
