摘要
原发性肝细胞癌是全世界常见的恶性肿瘤之一,每年一半的新发肝癌发生在中国。大量临床研究和实践证明早筛和早诊可有效降低肝癌的5年总病死率。因此探索建立适合中国国情的肝癌筛查策略极其迫切。全国多中心前瞻性肝癌极早期预警筛查项目(Prospective suRveillance for very Early hepatoCellular cARcinoma,PreCar)专家组基于国内外主要相关指南、临床实践和PreCar项目研究最新进展,提出了中国早期肝癌筛查策略和具体流程,旨在为早期肝癌筛查和诊断提供实际方法,提高我国防控水平。
Primary hepatocellular carcinoma is one of the most common malignancies worldwide.Half of the annual newly diagnosed liver cancer cases come from China.A large number of clinical studies and practices have proved that early screening and early diagnosis can effectively reduce the 5-year total mortality of liver cancer.Therefore,it is extremely urgent to explore and establish customized liver cancer screening strategies for China.Based on the relevant domestic and foreign guidelines,clinical practice,and the latest advances in the research of the PreCar project,the expert from PreCar project(Prospective suRveillance for very Early hepatoCellular cARcinoma,PreCar),proposed novel strategies and procedures for early liver cancer screening in my country.The PreCar project aims to provide practical methods for early liver cancer screening and diagnosis,and to improve our national prophylactic level for liver cancer.
作者
全国多中心前瞻性肝癌极早期预警筛查项目(PreCar)专家组
王红阳
侯金林
王传新
樊蓉
陈磊
杜鲁涛
钱云松
汪慧
Prospective suRveillance for very Early hepatoCellular cARcinoma(PreCar)expert panel;Wang Hongyang;Hou Jinlin;Wang Chuanxin(不详;National Center for Liver Cancer,Shanghai 210822,China;Nanfang Hospital Southern Medical University,Guangzhou 510515,China;The Second Hospital of Shandong University,Jinan 250033,China)
出处
《中华肝脏病杂志》
CSCD
北大核心
2021年第6期515-522,共8页
Chinese Journal of Hepatology
基金
国家重点研发计划蛋白质机器与生命过程调控重点项目(2017YFA0505803,2017YFC0908100)
传染病防治科技重大专项(2018ZX10732202001、2018ZX10302207004)
国家自然科学基金(81790633、81988101、91859205、81830054)
上海市自然科学基金(17ZR143800、201901070007E00065)
深圳市医药卫生"三名工程"高层次医学团队项目(SZSM201911001)
广东省"珠江人才计划"本土创新科研团队项目(2017BT01S131)
重庆市科技局项目:慢乙肝患者抗病毒治疗复发后细胞毒性T细胞的研究(cstc2017jcyjAX0398)。
关键词
肝细胞癌
筛选策略
专家共识
Hepatocellular carcinoma
Screening strategy
Expert consensus