摘要
In a recent report in Science,McCarthy et al.promptly observed a pattern of recurrent deletions in four discrete regions of the N-terminal Domain(NTD)of the Spike protein,which provide resistance to antibody neutralization,suggesting convergent evolution due to selective pressure and antigenic drift.
基金
M.R.and C.Ch.received salary support from Unitaid through the BOHEMIA grant to ISGlobal.ISGlobal acknowledges support from the Spanish Ministry of Science and Innovation through the“Centro de Excelencia Severo Ochoa 2019-2023”Program(CEX2018-000806-S)
support from the Generalitat de Catalunya through the CERCA Program.