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Adapt or perish:SARS-CoV-2 antibody escape variants defined by deletions in the Spike N-terminal Domain

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摘要 In a recent report in Science,McCarthy et al.promptly observed a pattern of recurrent deletions in four discrete regions of the N-terminal Domain(NTD)of the Spike protein,which provide resistance to antibody neutralization,suggesting convergent evolution due to selective pressure and antigenic drift.
出处 《Signal Transduction and Targeted Therapy》 SCIE CSCD 2021年第5期1416-1417,共2页 信号转导与靶向治疗(英文)
基金 M.R.and C.Ch.received salary support from Unitaid through the BOHEMIA grant to ISGlobal.ISGlobal acknowledges support from the Spanish Ministry of Science and Innovation through the“Centro de Excelencia Severo Ochoa 2019-2023”Program(CEX2018-000806-S) support from the Generalitat de Catalunya through the CERCA Program.
关键词 al. PROMPT Domain
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