左侧肺癌切除联合区域淋巴结清扫手术病人淋巴结转移与临床病理的关系分析

Relationship between lymph node metastasis and clinical pathology in patients with left lung cancer resection combined with regional lymph node dissection

目的分析左侧肺癌切除联合区域淋巴结清扫手术淋巴结转移规律与临床病理的关系。方法 2017年2月~2019年2月我院收治的行左侧肺癌切除联合区域淋巴结清扫术病人90例,分析淋巴结转移规律和危险因素相关性。结果左肺上叶转移数高于左肺下叶,差异有统计学意义(P<0.05)。小细胞癌转移数高于腺癌和鳞癌,鳞癌高于腺癌,差异有统计学意义(P<0.05)。T3高于T1、T2、T4,T2高于T1、T4,T4高于T1,差异有统计学意义(P<0.05)。低分化转移数高于高分化和中分化,中分化高于高分化,差异有统计学意义(P<0.05)。左上肺总转移率为29.76%,其中第3组和第10组最多;左下肺总转移率为20.92%,来自于第6组最多。结论左上肺易转移至第3、10组淋巴结,左下肺易转移至第6组淋巴结,同时转移的危险因素与肿瘤大小、病理分型、肿瘤部位、病理分化程度有关,与年龄、吸烟、性别无关。

Objective To investigate the relationship between lymph node metastasis and r and clinical pathology in patients with left lung cancer resection combined with regional lymph node dissections.Methods A retrospective analysis of 90 patients with left lung cancer resection combined with regional lymph node dissection in our hospital from February 2017 to February 2019 Patients was performed.Pathological analysis of the patient’s clinical data and analysis of the correlation between lymph node metastasis and risk factors.Results The number of metastases in upper lobe of left lung was higher than that in lower lobe of left lung(P<0.05).The number of small cell carcinoma metastases was significantly higher than that of adenocarcinoma and squamous cell carcinoma, and squamous cell carcinoma was significantly higher than adenocarcinoma(P<0.05).T3 was significantly higher than T1,T2,T4,while T2 was significantly higher than T1,T4,and T4 significantly higher than T1(P<0.05).The number of poorly differentiated metastases was significantly higher than that of the high differentiated and moderately differentiated, and moderately differentiated was significantly higher than high differentiated(P<0.05).The total left upper lung metastasis rate was 29.76%,of which groups 3 and 10 were the most;the total left inferior lung metastasis rate was 20.92%,of whichgroup 6 the most.Conclusions The upper left lung is easily metastasized to lymph nodes in groups 3 and 10,the left middle lung is easily metastasized to lymph nodes in group 3,and the inferior left lung is easily metastasized to lymph nodes in 6 groups.At the same time, the risk factors for metastasis are related to tumor size, pathological classification, tumor location, and degree of pathological differentiation, and not to patient age, smoking, and gender.