Force CT评价下肢深静脉血栓CT值与血液成分的关系

A clinical study on the relationship between CT value of DVT and blood components by Force CT

目的探讨下肢深静脉血栓(deep vein thrombosis, DVT)病人Force CT能谱成像中血栓CT值与血液成分的关系,分析血栓CT值的影响因素。方法 2015年12月~2017年1月疑似下肢深静脉血栓病人21例。所有受试者空腹后经肘静脉注入对比剂进行SOMATOM Force CT扫描,观察CT图像上血管、血栓形态及血栓分布,使用能谱软件获得40~190 Kev图像。测量选取的ROI在各单能量图像中的值。测定所有受试者血液中血红蛋白、红细胞、血小板。运用SPSS分析软件多元逐步回归分析法确定各单能量下的血栓与正常腿静脉血液CT值与上述血液成分的关系。结果在40~190 Kev中,只有血红蛋白与血液CT值有统计学关系。血栓CT能谱曲线与CT值的关系:40~190 Kev单能量,血液CT值与红细胞、血红蛋白、血小板建立回归方程,所有的回归方程均无统计学意义(F=1.12~3.14,P>0.05),显示血栓中能谱血液CT值与红细胞、血红蛋白、血小板无明显相关性。结论在正常血液中,血红蛋白是影响血液CT值的主要因素,而红细胞和血小板对血液CT值影响不显著;血栓中能谱CT值与红细胞、血红蛋白、血小板无明显相关性。

Objective This study is to explore the relationship between blood components and thrombosis CT imaging of the(Deep vein thrombosis)DVT by Force CT spectrum, clarify the influence factors of thrombosis CT value, early evaluation on the study of thrombus stability.Methods Analysis of 21 patients with suspected lower extremity deep venous thrombosis was conducted from Dec, 2015 to Jan, 2017.Scanning all the patients by SOMATOM Force CT after the injection of contrast agent in the elbow vein, recording vessel and thrombus shape, thrombus distribution and collateral vessels on CT enhanced image.Reconstructed the image and uploaded the data to the workstation.The 40-190 Kev of Energy spectrum image can be obtained by energy spectrum analysis software.All the subjects were tested for hemoglobin, red blood cells and platelets.SPSS regression analysis was used to determine the relationship between the CT value of each single energy and the blood components.Results According to the 40-190 Kev, among red blood cell, hemoglobin and platelet, only hemoglobin has statistical relationship with blood CT values, only hemoglobin has a significant influence on the CT value of blood.The relationship between thrombosis CT spectrum curve of thrombus and blood components: through multiple stepwise regression analysis showed that regression equation between 40-190 Kev single energy thrombus CT and red blood cells, hemoglobin, platelet were no significant difference in all the regression equations(F=1.12~3.14,P>0.05),there was no obvious correlation between spectrum CT value of thrombus and red blood cells, hemoglobin, platelet.Conclusion In normal blood, hemoglobin is the main factors influencing the CT value of blood, while red blood cells and platelets of blood CT value had no significant influence;there are no significant correlation between thrombosis and energy spectrum and CT value of blood red blood cells, hemoglobin, platelet.