鼻内镜下Messerklinger手术对真菌性鼻-鼻窦炎患者的疗效及对血清炎性因子水平的影响

Effect of Meserklinger Operation under Nasal Endoscope in Patients with Fungal Rhinosinusitis and Its Influence on Serum Inflammatory Factors

目的:观察鼻内镜下Messerklinger手术对真菌性鼻-鼻窦炎患者的疗效及对其血清炎性因子水平的影响。方法:将在笔者所在医院(2016年8月-2020年10月)就诊的真菌性鼻-鼻窦炎患者60例纳入研究,随机数字表法进行分组,每组30例。选取其中30例实施传统鼻内镜手术治疗设置为对照组,选取另30例实施鼻内镜下Messerklinger手术设置为试验组。对照两组患者治疗前后血清炎症指标水平、术后并发症及临床治疗疗效。结果:治疗前血清炎性指标水平比较,差异无统计学意义(P>0.05)。治疗后较治疗前明显降低,且试验组低于对照组,差异有统计学意义(P<0.05)。试验组患者术后并发症(6.67%)低于对照组(33.33%),差异有统计学意义(P<0.05)。试验组患者总控制率(100%)高于对照组(93.33%),但差异无统计学意义(P>0.05)。结论:在真菌性鼻-鼻窦炎患者的治疗中,实施以鼻内镜下Messerklinger手术可获得与传统手术相媲美的疗效,但是较传统手术,更可以明显降低机体内的血清炎症因子水平,减少术后并发症。

Objective:To observe the curative effect of Meserklinger operation under nasal endoscope in patients with fungal rhinosinusitis and its influence on the level of serum inflammatory factors.Method:A total of 60 patients with fungal rhinosinusitis were treated in our hospital from August 2016 to October 2020,and they were randomly divided into 2 groups with 30 cases in each group.Among them,30 cases were set as the control group of traditional endoscopic nasal surgery and the other 30 cases were set as the experimental group of Meserklinger operation under nasal endoscope.The levels of serum inflammatory indexes,postoperative complications and clinical curative effect were compared between the two groups before and after treatment.Result:There was no significant difference in serum inflammatory index before treatment (P>0.05).After treatment,serum inflammatory index were lower than before,those of experimental group were lower than control group,the difference was significant (P<0.05).The postoperative complications of the experimental group (6.67%) was lower than 33.33% of the control group,the difference was statistically significant (P<0.05).The total control rate of the experimental group (100%) was higher than 93.33% of the control group,but the difference was not statistically significant (P>0.05).Conclusion:In the treatment of patients with fungal rhinosinusitis,the implementation of Meserklinger operation under nasal endoscope can achieve the same effect as the traditional operation,but compared with the traditional operation,it can significantly reduce the level of serum inflammatory factors in the body,reduce the incidence of postoperative complications,the effect is ideal.