Vitapex糊剂行根尖诱导术治疗年轻恒牙根管感染患儿的效果

Effect of Vitapex Paste on Apical Induction in Children with Root Canal Infection of Young Permanent Teeth

目的:探讨Vitapex糊剂行根尖诱导术治疗年轻恒牙根管感染患儿的效果。方法:选取2016年4月-2018年7月北京市丰台区妇幼保健院116例年轻恒牙根管感染患儿,按照随机数字表法分为两组,对照组(n=58)给予氢氧化钙糊剂治疗,观察组(n=58)给予Vitapex糊剂治疗。观察两组治疗效果、龈沟液炎症因子、疼痛程度、根尖发育情况及不良反应情况。结果:观察组有效率(98.28%)高于对照组(87.93%)(P<0.05);观察组肿瘤坏死因子、白介素-8及白介素-1水平低于对照组(P<0.05);观察组EIP评分优于对照组(P<0.05);观察组根尖孔宽度小于对照组,牙根长度长于对照组,根管壁厚度大于对照组(P<0.05),不良反应发生率(3.44%)与对照组(5.16%)对比差异无统计学意义(P>0.05)。结论:Vitapex糊剂行根尖诱导术治疗年轻恒牙根管感染可有效改善患儿龈沟液炎症水平及根尖发育情况,降低疼痛程度,从而提高治疗效果,且不会增加不良反应。

Objective:To explore the effect of Vitapex paste on apical induction in children with young permanent teeth root canal infection.Method:A total of 116 children with root canal infection of young permanent teeth in Fengtai District Maternity and Child Health Hospital of Beijing from April 2016 to July 2018 were selected and divided into two groups according to random number table method.The control group(n=58)was treated with calcium hydroxide paste,and the observation group(n=58)was treated with Vitapex paste.The treatment effect,inflammatory factors in gingival crevicular fluid,degree of pain,apical development and adverse reactions were observed.Result:The effective rate of the observation group(98.28%)was higher than that of the control group(87.93%)(P<0.05);the levels of tumor necrosis factor,interleukin-8 and interleukin-1 of the observation group were lower than those of the control group(P<0.05);EIP score of the observation group was better than the control group(P<0.05);the width of the apical hole of the observation group was smaller,the root length was longer,and the thickness of the root canal wall was greater than than of the control group(P<0.05),the incidence of adverse reactions of the observation group(3.44%)was compared with the control group(5.16%),and the difference was not statistically significant(P>0.05).Conclusion:Vitapex paste apex induction for the treatment of root canal infections of young permanent teeth can effectively improve the inflammation level of gingival crevicular fluid and root apex development in children,reduce the degree of pain,thereby improve the treatment effect,and will not increase the occurrence of adverse reactions.