小剂量丙泊酚治疗40例老年人术后谵妄的临床观察

Clinical Observation of Low-dose Propofol in the Treatment of 40 Elderly Patients with Postoperative Delirium

目的:总结分析小剂量丙泊酚治疗老年人术后谵妄的临床效果。方法:选择本院2019年6月-2020年7月收治的80例术后谵妄的老年患者为研究对象,根据治疗中所用药物的差异性来分组,观察组和对照组各40例,分别应用丙泊酚、氟哌利多进行治疗。再以ICDSC(重症澹妄筛查表)评估治疗效果,记录两组住院时间、并发症发生率(低血压、心动过缓、气管插管等)。结果:治疗后观察组ICDSC评分(1.8±0.3)分,明显低于对照组,差异有统计学意义(P<0.05);观察组并发症发生率15.00%,明显低于对照组的35.00%,差异有统计学意义(P<0.05);观察组住院时间(2.9±1.3)d,明显短于对照组,差异有统计学意义(P<0.05)。结论:小剂量丙泊酚治疗老年人术后谵妄的临床效果显著,且并发症少,值得推广使用。

Objective:To summarize and analyze the clinical effects of low-dose propofol in the treatment of postoperative delirium in the elderly.Method:A total of 80 elderly patients with postoperative delirium admitted to our hospital from June 2019 to July 2020 were selected as the research objects,and they were grouped according to the difference of the drugs used in the treatment.Observation group and control group each had 40 cases,respectively.Propofol and droperidol were used for treatment.Then ICDSC(Severe Delusion Screening Form)was used to evaluate the treatment effect,and the hospital stay and the incidence of complications(hypotension,bradycardia,endotracheal intubation,etc.)were recorded in the two groups.Result:After treatment,the ICDSC score of the observation group was(1.8±0.3),which was significantly lower than that of the control group,and the difference was statistically significant(P<0.05);the complication rate of the observation group was 15.00%,which was significantly lower than 35.00%of the control group.The difference was statistically significant(P<0.05);the hospital stay in the observation group was(2.9±1.3)days,which was significantly shorter than that of the control group,and the difference was statistically significant(P<0.05).Conclusion:The clinical effect of low-dose propofol in the treatment of postoperative delirium in the elderly is significant,and there are few complications.It is worthy of popularization.