天王补心丹加减治疗心肾不交型围绝经期失眠25例疗效观察

Observation on treating 25 cases of perimenopausal insomnia due to disharmony between heart and kidney with Tianwang Buxin Dan

目的:观察天王补心丹加减治疗围绝经期失眠的临床疗效。方法:50例研究对象随机分为对照组和治疗组,对照组给予西医常规治疗,治疗组给予西医常规治疗加天王补心丹加减口服治疗,比较临床效果。结果:治疗组总有效率明显高于对照组,差异具有统计学意义(P<0.05);治疗后治疗组睡眠质量、入睡时间、睡眠时间、睡眠效率、睡眠障碍、日间功能障碍评分明显低于同期对照组,差异有统计学意义(P<0.05);治疗后治疗组患者失眠、心烦心悸、五心烦热、耳鸣头晕、潮热出汗评分明显低于对照组,差异有统计学意义(P<0.05);治疗组不良反应发生率明显低于对照组,差异具有统计学意义(P<0.05)。治疗前两组患者神经功能评分的差异无统计学意义(P>0.05),治疗后治疗组明显低于对照组(P<0.05)。结论:天王补心丹加减治疗围绝经期失眠的临床效果显著,能有效改善神经功能、睡眠质量。

Objective:To observe the clinical efficacy of Tianwang Buxin Dan(天王补心丹)on perimenopausal insomnia.Methods:50 cases were selected as the research objects and were randomly divided into the control group and the treatment group.The control group was given conventional Western medicine,and the treatment group was given conventional Western medicine plus Tianwang Buxin Dan.Results:The total efficiency in the treatment group was significantly higher than that in the control group(P<0.05).After treatment,the scores of sleep quality,falling asleep time,sleep time,sleep efficiency,sleep disturbance,and day dysfunction in the treatment group were significantly lower than the control group during the same period(P<0.05).After treatment,the scores of insomnia,upset and palpitation,hot,tinnitus,dizziness,hot flashes and sweating in the treatment group were significantly lower than the control group,P<0.05.The incidence of adverse reactions in the treatment group was significantly lower than the control group,P<0.05.After treatment,the neurological function scores in the treatment group was significantly lower than the control group(P<0.05).Conclusion:Tianwang Buxin Dan shows a significant clinical effect on perimenopausal insomnia,and it can effectively improve neurological function and sleep quality.