舒芬太尼与丙泊酚联合治疗在小儿麻醉临床治疗中的价值

Value of sufentanil combined with propofol in clinical treatment of pediatric anesthesia

目的探讨舒芬太尼与丙泊酚联合治疗在小儿麻醉临床治疗中的价值。方法110例需要进行麻醉治疗的患儿,按照随机分组发分为对照组和观察组,每组55例。对照组患儿采用舒芬太尼注射液进行麻醉诱导治疗干预,观察组采用舒芬太尼与丙泊酚联合麻醉诱导治疗干预。比较两组患者呼吸循环功能水平、麻醉效果、术后恢复情况以及不良反应发生情况。结果观察组患儿心率(82.35±3.79)次/min、气道压力(17.68±0.87)cm H2O(1 cm H2O=0.098 kPa)、血氧饱和度(98.56±4.28)%均优于对照组的(89.47±4.58)次/min、(13.07±0.56)cm H2O、(90.73±5.16)%,差异具有统计学意义(P<0.05)。观察组麻醉有效率92.73%高于对照组的70.91%,差异具有统计学意义(χ^(2)=8.800,P=0.003<0.05)。观察组患儿苏醒时间、拔管时间、自主呼吸恢复时间分别为(16.27±2.16)、(14.08±1.93)、(13.15±1.72)min均短于对照组的(23.51±3.48)、(18.76±2.65)、(16.96±2.47)min,差异均具有统计学意义(t=13.109、10.587、9.388,P=0.000、0.000、0.000<0.05)。观察组不良反应发生率7.27%低于对照组的21.82%,差异具有统计学意义(χ^(2)=4.681,P=0.031<0.05)。结论在小儿麻醉临床治疗中,采用舒芬太尼与丙泊酚联合治疗干预具有更好的临床效果,能够有效改善患儿的呼吸循环功能、麻醉效果、术后恢复情况,并降低不良反应发生率,值得临床研究和推广。

Objective To discuss the value of sufentanil combined with propofol in clinical treatment of pediatric anesthesia.Methods A total of 110 children requiring anesthesia were divided into control group and observation group according to random grouping method,with 55 cases in each group.The control group received sufentanil injection for anesthesia induction,and the observation group received sufentanil and propofol combined anesthesia induction.The respiratory and circulatory function level,anesthesia effect,postoperative recovery,and occurrence of adverse reactions were compared between the two groups.Results The heart rate(82.35±3.79)beats/min,airway pressure(17.68±0.87)cm H2O(1 cm H2O=0.098 kPa)and blood oxygen saturation(98.56±4.28)%of the observation group were better than(89.47±4.58)beats/min,(13.07±0.56)cm H2O and(90.73±5.16)%of the control group,and the difference was statistically significant(P<0.05).The anesthesia effective rate 92.73%of the observation group was higher than 70.91%of the control group,and the difference was statistically significant(χ^(2)=8.800,P=0.003<0.05).The wake up time,extubation time,spontaneous breathing recovery time of the observation group were(16.27±2.16),(14.08±1.93)and(13.15±1.72)min,which were shorter than(23.51±3.48),(18.76±2.65)and(16.96±2.47)min of the control group,and the difference was statistically significant(t=13.109,10.587,9.388;P=0.000,0.000,0.000<0.05).The incidence of adverse reactions 7.27%of the observation group was lower than 21.82%of the control group,and the difference was statistically significant(χ^(2)=4.681,P=0.031<0.05).Conclusion Combination of sufentanil and propofol has better clinical effect on pediatric anesthesia,which can effectively improve the respiratory and circulatory function,anesthesia effect,postoperative recovery,and reduce the incidence of adverse reactions.It is worthy of clinical research and promotion.