颅内动脉瘤夹闭术与介入栓塞术后患者医院感染病原菌分布特点及预后分析

The Comparison of Pathogen Distribution and Complications in Intracranial Aneurysm Patients after Clamp Operation and Intervene Embolize Therapy

目的:本研究对颅内动脉瘤夹闭术后与介入栓塞术后医院感染病原菌分布特点及并发症对比进行分析,为临床治疗提供参考。方法:回顾性分析本院2016年1月~2019年10月期间诊治的280例颅内动脉瘤患者临床资料,全自动细菌鉴定与药敏系统分析患者经夹闭术(140例)与介入栓塞术(140例)后感染病原菌分布,并研究二组患者治疗后并发症的发生情况。结果:颅内动脉瘤夹闭术后患者感染病原菌共140株,其中革兰阳性菌78株占55.7%,以金黄色葡萄球菌(12.1%)、化脓性链球(10.7%)、粪肠球菌(7.1%)和G型溶血性链球菌(6.4%)为主,革兰阴性菌62株占44.3%,以铜绿假单胞菌(8.6%)、鲍氏不动杆菌(7.1%)、产气肠杆菌(7.1%)和肺炎克雷伯菌(5.7%)为主;栓塞术后患者感染病原菌共140株,其中革兰阳性菌76株占54.3%,以化脓性链球(14.3%)、F型溶血性链球菌(7.9%)、粪肠球菌(7.1%)和G型溶血性链球菌(5.7%)为主,革兰阴性菌64株占45.7%,以肺炎克雷伯菌(12.9%)、脑膜炎奈瑟菌(6.4%)、鲍氏不动杆菌(6.4%)和产气肠杆菌(5.0%)为主;颅内动脉瘤夹闭术后与介入栓塞术后患者并发症有脑血管痉挛、动脉瘤破裂、脑梗死、脑水肿、电解质紊乱和颅内感染等,但二组患者总并发症发生率无统计学的差异性;颅内动脉瘤夹闭术后治愈率、重度残障率低于介入栓塞组而预后良好率高于介入栓塞术组患者,而轻度残障和死亡率无明显差异性。结论:颅内动脉瘤夹闭术后与介入栓塞术后感染病原菌分布有一定差异性,而并发症发生率无差异性。

Objective The present tried to compare the pathogen distribution and complications in intracranial aneurysm patients after clamp operation and intervene embolize therapy.Methods 280 cases of intracranial aneurysm patients in our hospital from January 2016 to October 2019 were enrolled in this research.The pathogen distribution and complications in intracranial aneurysm patients after clamp operation and intervene embolize therapy.Results The result showed that 140 strains were isolated from the intracranial aneurysm patients after clamp operation.At the same time,140 strains were isolated from the intracranial aneurysm patients after intervene embolize therapy.The result also showed that the complications of intracranial aneurysm patients after clamp operation and intervene embolize therapy contained cerebral angiospasm,aneurysm rupture,cerebral infarction,encephaledema,electrolyte imbalance and cerebral infection.The results revealed that the adverse reaction in intracranial aneurysm patients after clamp operation and intervene embolize therapy showed no statistical differences.However,the cure rate and severe disability rate were lower while prognosis rate were higher in clamp operation than intervene embolize therapy patients.At the meaning time,there were no statistical differences of slight disability rate and death rate.Conclusion The pathogen kinds and distribution were different while complications showed no different in intracranial aneurysm patients after clamp operation and intervene embolize therapy.