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负荷剂量右美托咪定对肝移植受者术后24 h内MACE风险的影响 被引量:1

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摘要 目的探讨麻醉诱导后负荷剂量右美托咪定静脉输注、泵注对肝移植受者术后心肌酶及24 h内主要心血管事件(MACE)风险的影响。方法选取郑州人民医院2018年3月至2019年2月收治的52例肝移植受者,按照麻醉方法不同分为两组,各26例。对照组于麻醉诱导后静注等容量生理盐水,观察组于麻醉诱导后右美托咪定负荷静注,再泵注至手术结束。比较两组术前术后血清肌红蛋白(Mb)、肌钙蛋白I(cTnI)、肌酸激酶同工酶(CK-MB)水平及术后24 h内MACE发生率。结果术后,观察组血清Mb、cTnI、CK-MB水平高于对照组,差异有统计学意义(P<0.05);观察组室上性心动过速发生率(30.77%)低于对照组(61.54%),心肌缺血发生率(11.54%)低于对照组(38.46%),差异有统计学意义(P<0.05)。结论麻醉诱导后负荷剂量右美托咪定静脉输注、泵注应用于肝移植受者,可降低术后心肌酶水平、24 h内MACE风险。
作者 李海斌
出处 《临床研究》 2021年第7期89-90,共2页 Clinical Research
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