摘要
目的:探讨GCET1在弥漫大B细胞淋巴瘤(DLBCL)中的表达水平及其临床意义。方法:选择南方医科大学顺德医院2015年8月至2020年8月收治的DLBCL患者石蜡标本30例,采用免疫组化法检测GCET1的表达水平,并分析其与临床因素的关系。结果:30例DLBCL患者石蜡标本中GCET1蛋白的阳性表达率为33.3 %,其与患者淋巴瘤国际预后指数(IPI)评分、年龄调整国际预后指数(aa IPI)评分和Ann Arbor分期呈显著相关性,差异有统计学意义(P<0.05)。结论:GCET1蛋白在DLBCL患者中表达水平较高,Ann Arbor分期、aa IPI评分、IPI评分对该部分患者的预后具有较高的预测价值。
Objective To investigate the expression of gcet1 in diffuse large B-cell lymphoma (DLBCL) and its clinical significance.Methods Thirty paraffin embedded specimens of DLBCL patients in Shunde Hospital of Southern Medical University from August 2015 to August 2020 were selected.The expression level of gcet1 was detected by immunohistochemistry,and the relationship between gcet1 and clinical features was analyzed.Results The positive expression rate of gcet1 protein was 33.3%,which was significantly correlated with IPI score,AA IPI score and Ann Arbor stage (P < 0.05).Conclusion the expression level of gcet1 protein is high in DLBCL patients.Ann Arbor stage,AA IPI score and IPI score have high predictive value for the prognosis of DLBCL patients.
作者
吴亮
刘香
杨辉
WU Liang;LIU Xiang;YANG Hui(Shunde Hospital of Southern Medical University,Guangdong Foshan 528300)
出处
《深圳中西医结合杂志》
2021年第8期21-23,共3页
Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
