注射用丹参多酚酸治疗血管源性眩晕的疗效分析

Therapeutic effect of salvianolic acid for injection on vasogenic vertigo

目的探讨注射用丹参多酚酸治疗血管源性眩晕的临床疗效。方法选择2019年5月~2020年5月我院治疗的90例血管源性眩晕患者为研究对象,将患者随机分为对照组和观察组各45例。对照组给予天麻注射液+马来酸桂哌齐特治疗,观察组给予注射用丹参多酚酸+马来酸桂哌齐特治疗,观察两组患者的临床疗效、临床症状消失时间,并比较两组患者治疗前后眩晕残障程度量表(DHI)评分情况、缺血区域脑血流指数及不良反应发生情况。结果观察组的治疗总有效率高于对照组(P<0.05),临床症状消失时间早于对照组(P<0.05)。两组患者的DHI评分、缺血区域脑血流指数比较,治疗前两组患者比较差异均无统计学意义(均P>0.05);治疗后,观察组各项指标改善优于对照组,差异有统计学意义(P<0.05)。两组患者的不良反应发生率比较,观察组明显低于对照组,差异有统计学意义(P<0.05)。结论注射用丹参多酚酸治疗血管源性眩晕的效果明显,有助于改善患者眩晕障碍程度,控制病情发展,且不良反应低,值得临床推广。

Objective To investigate the clinical efficacy of salvianolic acid for injection in the treatment of vasogenic vertigo.Methods A total of 90 patients with vasogenic vertigo treated in our hospital from May 2019 to May 2020 were selected as the research subjects,and the patients were randomly divided into control group and observation group with 45 cases in each group.The control group given gastrodia elata injection+cinepazide maleate treatment,observation group was given with salvianolic acid injection+cinepazide maleate treatment,to observe the clinical efficacy of the clinical symptoms disappear time in two groups of patients,and compare the vertigo degree of disability scale(DHI)grading,index of regional cerebral blood flow,ischemia and adverse reactions occur in patients of two groups before and after treatment.Results The total effective rate of the observation group was higher than that of the control group(P<0.05),and the clinical symptoms disappeared earlier than that of the control group(P<0.05).There was no significant difference in DHI score and cerebral blood flow index in the ischemic area between the two groups before treatment(all P>0.05).After treatment,the improvement of each index in the observation group was better than that in the control group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions in two groups was significantly lower in observation group than control group,the difference was statistically significant(P<0.05).Conclusion Salvianolic acid for injection is effective in the treatment of vasogenic vertigo,which is helpful to improve the degree of vertigo disorder in patients and control the development of the disease.The adverse reactions are low and worthy of clinical promotion.