夏桂成教授治疗不孕症行经期用药特点分析

Analysis on the characteristics of menstrual period drug use in the treatment of infertility by Professor Xia Guicheng

目的了解夏桂成教授治疗不孕症行经期中药饮片处方用药,探索和研究其用药特点和规律。方法选取南京中医药大学附属医院2016年9月—2017年9月夏桂成教授治疗不孕症行经期中药饮片处方984张,进行数据整理,分析处方中高频药物、高频药对、归经及基础方剂,探索其用药特点。结果使用频率>10%的单味中药有赤芍、泽兰、麸炒苍术、丹参、醋香附、益母草、茯苓等20味,其中活血化瘀药使用频率最高,其次为理气药、清热药、化湿药、补虚药。26个高频药对包括赤芍与泽兰、赤芍与麸炒苍术、赤芍与丹参等。归肝经药物使用最多。基础方剂为麸炒苍术、赤芍、续断、丹参、茯苓、肉桂、醋香附、益母草、泽兰。结论夏桂成教授治疗不孕症行经期经常使用活血化瘀、理气、化湿、补虚等类药。行经期治法注重活血调经,补肾温阳,行气化湿。

Objective To understand Professor Xia Guicheng’s prescription drug use of traditional Chinese medicine decoction pieces in menstrual period in the treatment of infertility,and to explore and study the characteristics and rules of its drug use.Methods A total of 984 prescriptions of traditional Chinese medicine decoction pieces in menstrual period for infertility treated by Professor Xia Guicheng in Affiliated Hospital of Nanjing University of Chinese medicine from September 2016 to September 2017 were selected to conduct data sorting,and high-frequency drugs,high-frequency drug pairs,menstrual return and basic prescriptions in the prescriptions were analyzed to explore their characteristics of drug use.Results The single traditional Chinese medicine with the frequency of more than 10%included 20 herbs,such as Paeoniae Radix Rubra,Lycopi Herba,stir-baking with bran Atractylodis rhizoma,Salviae Miltiorrhizae;processing with vinegar Cyperi Rhizoma,Leonuri Herba and Poria.Among them,drugs for promoting blood circulation for removing blood stasis were used most frequently,followed by regulating qi-flowing drugs,heat-clearing drugs,eliminating dampness drugs and tonifying deficiency drugs.Twenty-six high-frequency drug pairs included Paeoniae Radix Rubra and Lycopi Herba,Paeoniae Radix Rubra and stir-baking with bran Atractylodis rhizoma,Paeoniae Radix Rubra and Salviae Miltiorrhizae,etc.Drugs belonging to the liver channel were used most.The basic formula was stir-baking with bran Atractylodis rhizoma,Paeoniae Radix Rubra,Dipsaci Radix,Salviae Miltiorrhizae,Poria,Cinnamomi Cortex,processing with vinegar Cyperi Rhizoma,Leonuri Herba,Lycopi Herba.Conclusion Professor Xia Guicheng often uses drugs such as promoting blood circulation for removing blood stasis,regulating qi-flowing,eliminating dampness and tonifying deficiency to treat infertility during menstrual period.Menstrual period treatment focuses on promoting blood circulation for regulating menstruation,tonifying the kidney and warming Yang,and activating qi flowing and eliminating dampness.