双源冠状动脉CTA在T2DM合并冠心病患者不同狭窄程度分级诊断中的应用价值

Application value of dual-source coronary CTA in the diagnosis of different grades of coronary stenosis in T2DM patients with coronary heart disease

目的探究双源冠状动脉CT血管造影(CTA)在2型糖尿病(T2DM)合并冠心病(CHD)患者不同狭窄程度分级诊断中的临床应用。方法将2017年4月—2020年4月安徽省淮南东方医院集团总院于收治的96例T2DM合并CHD患者作为研究对象。比较双源冠状动脉CTA、CAG诊断T2DM合并CHD患者不同狭窄程度分级的结果。分析双源冠状动脉CTA对T2DM合并CHD患者不同狭窄程度分级的诊断效能。结果两种方法在诊断不同狭窄程度分级比较,差异无统计学意义(P>0.05)。双源冠状动脉CTA在诊断冠状动脉轻微、轻度、中度、重度狭窄的AUC分别为0.823、0.801、0.794、0.928,灵敏度分别为80.00%、77.78%、83.33%、95.24%,特异性分别为99.37%、98.41%、98.37%、99.38%。结论双源冠状动脉CTA能够较为准确地对T2DM合并CHD患者的冠状动脉狭窄程度进行分级诊断,具有较高的诊断效能,是一种安全、高效、无创的检查手段。

Objective To research clinical application of dual-source coronary CT angiography(CTA)in the diagnosis of different grades of coronary stenosis in type 2 diabetes mellitus(T2DM)patients with coronary heart disease(CHD).Methods From April 2017 to April 2020,96 patients with T2DM and CHD in General Hospital of Huainan Eastern Hospital Group were selected as the research objects.The result of dual-source coronary CTA and CAG in the diagnosis of different grades of coronary stenosis in patients with T2DM and CHD were compared,and the diagnostic efficiency of dual-source coronary CTA in the diagnosis of different grades of coronary stenosis in patients with T2DM and CHD were analyzed.Results There was no significant difference in between the two methods in the different grades of coronary stenosis(P>0.05).The AUC of dual-source coronary CTA in the diagnosis of slight,mild,moderate and severe coronary stenosis were 0.823,0.801,0.794,0.928;and the sensitivity were 80.00%,77.78%,83.33%,95.24%,respectively;and the specificity were 99.37%,98.41%,98.37%and 99.38%,respectively.Conclusion Dual-source coronary CTA can accurately grade the degree of coronary stenosis in patients with T2DM and CHD.It has high diagnostic efficiency and is a safe,efficient and non-invasive examination method.