胸腔镜下三种手术方式治疗早期肺癌的疗效及对肺功能的影响研究

Curative efficacy of three types of thoracoscopic surgeryin treatment of Early lung cancerand its effectson lung function

目的:探讨胸腔镜下三种手术方式治疗早期肺癌的疗效及对肺功能的影响,为患者的临床手术治疗提供指导。方法:选择2015年8月~2018年8月我院接诊的早期肺癌患者90例作为研究对象,以随机数表法分为A组、B组、C组三组,各30例。A组采用胸腔镜辅助小切口肺叶切除术,B组采用开胸手术,C组采用胸腔镜肺段切除术。比较两组的手术时间、术中出血量、术后引流量、住院时间、第1秒用力呼气量(FEV1)、最大通气量(MVV)、用力肺活量(FVC)及不良反应发生情况。结果:C组患者手术时间、术中出血量、术后引流量及住院时间显著低于A组和B组;治疗前,三组患者MVV、FVC及FEV1水平无显著性差异;治疗后,三组患者MVV、FVC及FEV1水平均有所下降,但C组患者MVV、FVC及FEV1水平高于A组和B组,差异显著;治疗后,C组不良反应总发生率为6.67%、明显低于A组和B组的33.33%、20.00%。结论:早期肺癌患者采用胸腔镜肺段切除术优势明显,可有效缩短住院时间、减少不良反应发生情况,更好的保护患者肺功能,值得临床推广。

Objective To study Curative efficacy of three types of thoracoscopic surgeryin treatment of early lung cancerand its effectson lung function.Methods 90 cases of early stage lung cancer patients admitted to our hospital from August 2015 to August 2018 were selected as research objects,group A,group B and group C were divided into three groups with 30 cases each.Vats assisted small incision lobectomy was performed in group A,thoracotomy was performed in group B,and vats segmentectomy was performed in group C.The operative time,intraoperative blood loss,postoperative drainage volume,hospitalization time,forced expiratory volume in the first second (FEV1),maximum gas volume (MVV),forced vital capacity (FVC) and adverse reactions of the two groups were compared.Results The operative time,intraoperative blood loss,postoperative drainage and hospitalization time of group C were significantly lower than those of group A and group B.Before treatment,there was no significant difference in MVV,FVC and FEV1 levels among the three groups.After treatment,the levels of MVV,FVC and FEV1 in the three groups decreased,but the levels of MVV,FVC and FEV1 in group C were higher than those in group A and group B,with significant differences.After treatment,the total incidence of adverse reactions in group C was 6.67%,significantly lower than the 33.33% and 20.00% in group A and group B.Conclusion The advantages of thoracoscopic segmentectomy for patients with early lung cancer are obvious,which can effectively shorten the length of hospitalization,reduce the incidence of adverse reactions,and better protect the pulmonary function of patients,which is worthy of clinical promotion.