孕晚期宫内生长受限胎儿彩色多普勒血流显像相关参数变化及临床意义

The changes and clinical significance of parameters related to fetal color Doppler flow imaging with fetal growth restriction in late pregnancy

目的:探究孕晚期宫内生长受限胎儿的彩色多普勒血流现象相关参数变化及临床意义。方法:选择2018年8月~2020年1月我院收治67例孕晚期FGR产妇作为FGR组,另选择同期50例正常分娩的孕晚期孕妇作为对照组。产前行彩色多普勒超声检查,测量各血管的RI、PI和S/D等血流显像相关参数。结果:FGR组MCA的RI、RI和S/D值分别为(0.66±0.11)、(0.97±0.26)、(2.94±0.71),均明显低于对照组,FGR组UA、DV及UtA的RI、RI和S/D值分别为[(0.69±0.18)、(1.18±0.26)、(3.41±0.73)],[(0.62±0.14)、(1.15±0.33)、(3.58±0.82)],[(0.54±0.15)、(0.81±0.19)、(2.11±0.56)],均明显高于对照组,差异有统计学意义。Apgar≤7分组MCA的RI、RI和S/D值分别为(0.63±0.09)、(0.91±0.15)、(2.86±0.49),均明显低于Apgar>7分组(分别为(0.81±0.13)、(1.46±0.32)、(4.58±0.71)),Apgar≤7分组UA、DV及UtA的RI、RI和S/D值分别为[(0.73±0.14)、(1.23±0.27)、(3.46±0.64)],[(0.69±0.17)、(1.17±0.26)、(3.66±0.71)],[(0.61±0.14)、(0.84±0.19)、(2.18±0.44)],均明显高于Apgar>7分组(分别为[[(0.54±0.11)、(0.89±0.16)、(2.11±0.33)],[(0.47±0.08)、(0.64±0.15)、(1.96±0.46)],[(0.36±0.06)、(0.53±0.11)、(1.71±0.28)]),差异有统计学意义。结论:孕晚期FGR发生时,胎儿各血管的血流参数均会出现异常改变,且与宫内生长受限程度密切相关,对于其临床诊治及妊娠结局的预测都具有重要价值。

Objective To research the changes and clinical significance of parameters related to fetal color Doppler flow imaging with fetal growth restriction in late pregnancy.Method From August 2018 to January 2020,67 FGR pregnant women in our hospital were selected as the FGR group,and 50 normal delivery pregnant women in the same period were selected as the control group.The parameters of RI,PI and S/D were measured.Result The RI,RI and S/D of MCA in FGR group were (0.66±0.11),(0.97±0.26),(2.94±0.71),respectively,thoses were significantly lower than those in control group,the RI,RI and S/D values of UA,DV and UtA in FGR group were [(0.69±0.18),(1.18±0.26),(3.41±0.73)],[(0.62±0.14),(1.15±0.33),(3.58±0.82)],[(0.54±0.15),(0.81±0.19),(2.11±0.56)],respectively,those were significantly lower than those in control group,the differences wee statistically significant.The RI,RI and S/D of MCA in the Apgar≤7 group were (0.63±0.09),(0.91±0.15),(2.86±0.49),respectively,thoses were significantly lower than those in the Apgar>7 group ((0.81±0.13),(1.46±0.32),(4.58±0.71),respectively),the RI,RI and S/D values of UA,DV and UtA in the Apgar≤7 group were [(0.73±0.14),(1.23±0.27),(3.46±0.64)],[(0.69±0.17),(1.17±0.26),(3.66±0.71)],[(0.61±0.14),(0.84±0.19),(2.18±0.44)],respectively,thoses were significantly lower than those in the Apgar>7 group ([(0.54±0.11),(0.89±0.16),(2.11±0.33)],[(0.47±0.08),(0.64±0.15),(1.96±0.46)],[(0.36±0.06),(0.53±0.11),(1.71±0.28)],respectively),the differences wee statistically significant.Conclusion When FGR occurs in late pregnancy,the blood flow parameters of blood vessels will change abnormally,and the abnormal changes are closely related to the degree of intrauterine growth restriction,which is of great value for clinical diagnosis and treatment and prediction of pregnancy outcome.