7例成人双肾移植的近期临床效果分析

Short-term outcomes of dual kidney transplantations in adults:a report of 7 cases

目的总结7例成人双肾移植的近期临床效果,分析其安全性和可行性。方法 2018年9月至2019年9月,华中科技大学同济医学院附属协和医院泌尿外科共完成7例成人双肾移植,回顾性分析7例成人双肾移植供、受者基线特征,临床数据以及术后并发症情况。结果 7例供者年龄(62.7±8.5)岁,受者年龄(43.9±9.3)岁,其中6对供肾Remuzzi评分为4~6分。7例成人双肾移植的移植肾及受者存活率均为100%,中位随访时间16个月。6例受者肾功能在1周内恢复正常,1例受者发生移植肾功能延迟恢复。7例成人双肾移植均采用双肾移植于单侧的手术方式,手术时间(5.6±1.4)h,未发生外科并发症。1例受者发生未经穿刺证实的排斥反应,3例受者发生肺部感染,其中1例重症肺炎。3例受者外侧移植肾血浆流量大于内侧。结论成人双肾移植是安全、可行的,有利于扩大供肾来源。

Objective To explore the short-term outcomes of dual kidney transplantation and summarize its safety and feasibility.Methods From September 2018 to September 2019,a total of 7 dual kidney transplantations were performed.And retrospective analysis was performed for baseline profiles,clinical data and postoperative complications.Results The mean age was(62.7±8.5)years for donors and(43.9±9.3)years for recipients.The Remuzzi score of 6 paired kidneys ranged from 4 to 6 points.During follow-ups,the survival rate of 7 dual kidney transplantation grafts and recipients was 100%.The median follow-up period was 16 months.Renal function of 6 recipients normalized within 1 week and delayed graft function(DGF)occurred in one case.All of them underwent unilateral kidney transplantation with an average operative duration of(5.6±1.4)hours.There was no onset of operative complications.One case of rejection was not confirmed by biopsy.Among three patients of lung infections,there was one case of severe pneumonia.In 3 cases,lateral plasma flow of transplanted kidney exceeded that of medial plasma flow.Conclusions Dual kidney transplantation in adults is both safe and feasible so as to expand the availability of donated kidney.