期刊文献+

非布司他对慢性肾脏病3~5期伴高尿酸血症患者氧化应激 反应的抑制作用 被引量:6

下载PDF
导出
摘要 慢性肾脏病(CKD)指的是多种因素引起的肾脏结构功能异常现象,随着人口老龄化趋势的不断加剧,其发病率逐年攀升。流行病学调查研究发现,CKD患者多伴随氧化应激水平升高,随着病情的进展,血管内皮损伤也会逐渐加重,发展至3~5期即慢性肾衰竭^([1]),患者伴随机体内环境失衡及肾功能减退,严重威胁患者生命安全。
出处 《中国药物与临床》 CAS 2021年第12期2129-2131,共3页 Chinese Remedies & Clinics
  • 相关文献

参考文献10

二级参考文献69

  • 1Park SH,Shin WY, Lee EY, et al. The impact of hyperurice-mia on in-hospital mortality and incidence of acute kidney inju-ry in patients undergoing percutaneous coronary intervention[Jl. Circulation Journal, 2011,75(3): 692-697.
  • 2Kansui Y,Ohtsubo T,Goto K, et al. Association of serum u-ric acid with blood pressure in Japanese men: Cross-sectionalstudy in work-site group [J]. Circulation Journal f 2011, 75(12): 2827-2832.
  • 3Fagugli RM, Gentile G,Ferrara G, et al. Acute renal and he-patic failure associated with allopurinol treatment [ J]. ClinNephrol, 2008,70(6): 523*526.
  • 4Halevy S,Ghislain PD, Mockenhaupt M,et al. Allopurinol isthe most common cause of Stevens-Johnson syndrome and tox-ic epidermal necrolysis in Europe and Israel[J]. Journal of theAmerican Academy of Dermatology? 2008,58(1): 25-32.
  • 5Becker MA, Schumacher HR, Wortmann RL, et al. Febux-ostat compared with allopurinol in patients with hyperuricemiaand gout[J]. N Engl,2005, 353(353): 2450-2461.
  • 6Akira Sezai, Masayoshi Soma, Kin-ichi Nakata, et al. Com-parison of Febuxostat and Allopurinol for Hyperuricemia in(8): 2043-2049.
  • 7Matsumoto K, Okamoto K. Ashizawa N, et al. FYX-051 : Anovel and potent hybrid-type inhibitor of xanthine oxidoreduc-tase[J]. Journal of Pharmacology Experimental Therapeu-tics, 2010, 336(1): 95-103.
  • 8Burns CM, Wortmann RL. Gout therapeutics: New drugs foran old disease[J]. Lancet, 2011, 377(9760) : 165-t77.
  • 9Tatuo H, Iwao O. A repeated oral administration study of fe-buxostat (TMX-67), a non-purine-selective inhibitor of xan-thine oxidase in patients with impaired renal function in Japan:pharmacokinetic and pharmacodynamic study [J]. Journal ofClinical Rheumatology Practical Reports on Rheumatic &-Musculoskeletal Diseases,2011,17(4 Suppl 2) : 27-34.
  • 10European Medicines Agency. AdenuricTM ( febuxostat) : EP-AR-product information[EB/OL], [2011-01-22].

共引文献138

同被引文献59

引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部