临床药师对肿瘤科应用蔗糖铁注射液115例评价分析

Evaluation and analysis of 115 cases of application of sucrose iron injection by clinical pharmacists in oncology department

目的考察某肿瘤科蔗糖铁注射液不合理用药问题,为促进临床合理用药水平提供科学管理依据。方法调取阜阳市第二人民医院肿瘤科2018年3月至2019年2月出院病人所有使用蔗糖铁注射液病历115份,参考《肿瘤相关性贫血临床实践指南》《2019年版静脉铁剂应用中国专家共识》、蔗糖铁注射液说明书和相关文献,从蔗糖铁注射液用药指征、给药疗程、用法用量和溶媒选择等方面进行专项点评。结果115例中,用药指征适宜率为93.91%,按照规定试验要求皮试适宜为96.52%,用药疗程合适率为40.00%,给药剂量合适率为91.30%,用药频次适宜率为0.00%,溶媒选择适宜率为100.00%,配制浓度适宜率为86.96%,平均用药疗程为8.5 d。结论某肿瘤科蔗糖铁注射液不合理使用现象较严重;临床药师应加强对肿瘤科蔗糖铁注射液医嘱点评力度,及时干预潜在用药问题。

Objective To investigate the irrational use of sucrose iron injection in Department of Oncology,and to provides a scientific management basis for improving the level of clinical rational medication.Methods Totally 115 medical records of the use of iron sucrose injection in the Department of Oncology,the Second People’s Hospital of Fuyang City from March 2018 to February 2019 were collected.The indications of iron sucrose injection,the course of administration,the usage and dosage,and the choice of solvents and other aspects were given special comments by referring to"Clinical Practice Guidelines for Tumor-related Anemia","Chinese Expert Consensus on the Application of Intravenous Iron in 2019 Edition",instructions for iron sucrose injection and related literature.Results ments was 96.52%.The suitable course of administration was 40.00%,the appropriate dosage was 91.30%,and the appropriate frequency was 0.00%,the suitable solvent selection was 100.00%and the suitable concentration was 86.96%.The average course of treatment was 8.5 days.Conclusion The unreasonable use of iron sucrose injection in a certain oncology department of hospital is more serious.Clinical pharmacists should strengthen their comments on the doctor’s orders of iron sucrose injection in the department of oncology and timely intervene potential medication problems.