小儿推拿结合麻杏银翘散加减治疗缓解期肺炎患儿的疗效

Clinical effects of infantile massage combined with modified Maxing Yinqiao Powder on the treatment of children with pneumonia during remission

目的探究小儿推拿结合麻杏银翘散加减治疗小儿肺炎咳嗽风热闭肺证的疗效。方法选择2016年1月—2019年1月台州市中医院收治的80例缓解期风热闭肺证肺炎患儿,采用随机数字表法分为2组,各40例。对照组给予西医治疗,观察组在此基础上采用小儿推拿结合麻杏银翘散加减治疗,测定T淋巴细胞亚群及血清炎症因子水平。结果(1)观察组及对照组总有效率分别为100.00%、95.00%;显效率为95.00%、77.50%(P<0.05)。(2)治疗后观察组临床体征[(4.71±1.41)分vs.(6.85±1.90)分]、中医证候积分[(2.85±0.56)分vs.(3.41±0.37)分]低于对照组(均P<0.05)。(3)治疗后观察组CD3^(+)、CD4^(+)T淋巴细胞亚群比例及CD4^(+)/CD8^(+)、白细胞介素-2(IL-2)水平高于对照组(均P<0.05),白细胞介素-6(IL-6)、肿瘤坏死因子(TNF-α)水平低于对照组(均P<0.05)。(4)观察组咳嗽消失时间[(8.01±1.04)d vs.(9.66±2.01)d]、气促消失时间[(1.56±0.27)d vs.(2.85±0.63)d]、肺啰音消失时间[(6.96±1.37)d vs.(8.56±1.74)d]及住院时间[(9.11±1.74)d vs.(11.22±1.63)d]短于对照组(均P<0.05)。结论小儿推拿结合麻杏银翘散治疗风热闭肺证肺炎具有较好的效果。

Objective To explore the curative effect of infantile massage combined with modified Maxing Yinqiao Powder on the treatment of infantile pneumonia with dyspnoeic cough of"wind-heat blocking the lung syndrome".Methods From January 2016 to January 2019,80 children with pneumonia of"wind-heat blocking the lung syndrome"during remission treated in Taizhou Hospital of Traditional Chinese Medicine(TCM)were enrolled in this study.They were randomly divided into two groups:the control group was treated with routine Western medicines,whereas the observation group was treated with infantile massage combined with modified Maxing Yinqiao Powder based on Western medicines treatment.Levels of T lymphocyte subsets and inflammatory factors were determined.Results The total effective rate in the observation and the control groups was 100.00%and 95.00%,respectively,and the markedly effective rate was 95.00%and 77.50%,respectively(P<0.05).After the treatment,the scores of clinical signs and TCM syndromes of the observation group[(4.71±1.41)points and(2.85±0.56)points,respectively]were significantly lower than those of the control group[(6.85±1.90)points and(3.41±0.37)points,respectively,all P<0.05].After the treatment,the proportions of CD3~+and CD4~+and levels of CD4~+/CD8~+and interleukin-2 in the observation group were higher than those in the control group(all P<0.05).The levels of interleukin-6 and tumour necrosis factor-αwere lower in the observation group than those in the control group(P<0.05).(4)The time for the shortness of breath and lung rales and cough to disappear,and the length of hospital stay in the observation group were(8.01±1.04),(1.56±0.27),(6.96±1.37)and(9.11±1.74)days,respectively of in the control group were(9.66±2.01),(2.85±0.63),(8.56±1.74)and(11.22±1.63)days,the difference was statistically significant(all P<0.05).Conclusion Infantile massage combined with modified Maxing Yinqiao Powder is effective in the treatment of infantile pneumonia with dyspnoeic cough of"wind-heat blocking the lung syndrome".