妊娠期母体肠道微生态调节对子代影响的研究进展

The effect of intestinal microecology regulation during pregnancy on offspring

妊娠期肠道微生态的调节受多重因素的影响,与母体的营养、代谢及免疫密切相关,与多种妊娠代谢性并发症有关,对子代肠道菌群的建立及远期健康有着深远的影响。本文对妊娠期肠道微生态的变化、子代肠道菌群的建立以及妊娠常见代谢疾病中肠道菌群的变化对子代的影响等方面进行综述,以期通过改善妊娠期肠道微生态结构,达到防治妊娠期不良的代谢状态及预防子代健康风险的目的。

The regulation of intestinal microecology during pregnancy is affected by multiple factors,which are closely related to maternal nutrition,metabolism and immunity,and are related to a variety of pregnancy metabolic complications,which has a profound impact on the establishment of the offspring intestinal flora and long-term health.This article will review and analyze the changes in the intestinal microbiota during pregnancy,the establishment of the intestinal flora of the offspring and the impact of the changes in the intestinal flora of the common metabolic diseases of pregnancy on the offspring.By improving the intestinal structure and preventing the poor metabolic state during pregnancy,the purpose of preventing health risks of offspring will be achieved.