{Ln^(Ⅲ)_(2)Co^(Ⅱ)_(6)}异金属配合物的合成及性质

Synthesis and Properties of {Ln^(Ⅲ)_(2)Co^(Ⅱ)_(6)} Heterometallic Complexes

以6⁃氯⁃2⁃羟基吡啶(Hcp)为配体,特戊酸(Hpiv)为辅助配体,设计合成了5例八核{Ln^(Ⅲ)_(2)Co^(Ⅱ)_(6)}(Ln=Sm(1)、Eu(2)、Tb(3)、Er(4)、Tm(5))异金属配合物。单晶结构表明配合物1~5为同构物,属于三斜晶系,空间群为P1。磁性测试表明,在配合物1~5中,反铁磁相互作用占主导作用。在抑菌性测试中,采用培养基扩散法测试配合物1~5及其同构物{Ln^(Ⅲ)_(2)Co^(Ⅱ)_(6)}(Ln=Dy(6)、Ho(7)、Gd(8)、Y(9))的抑菌作用。研究表明配合物1~9对大肠杆菌(E.coli)和金黄色葡萄球菌(S.aureus)都有一定的抑制作用。其中,配合物5对E.coli的抑菌效果最好,而配合物9对S.aureus的抑菌效果最好。

Using 6⁃chloro⁃2⁃hydropyridine(Hcp)as ligand and pivalic acid(Hpiv)as the auxiliary ligand,five heterometallic complexes{Ln^(Ⅲ)_(2)Co^(Ⅱ)_(6)}(Ln=Sm(1),Eu(2),Tb(3),Er(4),Tm(5))were synthesized.Single⁃crystal X⁃ray diffraction analyses reveal that complexes 1~5 are isostructural and belong to triclinic system space group P1.Magnetic susceptibilities revealed antiferromagnetic coupling within complexes 1~5,and complex 1 displayed slow relaxation of magnetization.Medium diffusion method was used to determine the antibacterial activity of complexes 1~5 and their isomorphisms{Ln^(Ⅲ)_(2)Co^(Ⅱ)_(6)}(Ln=Dy(6),Ho(7),Gd(8),Y(9)).All complexes possessed antibacterial activity on both escherichia coli(E.coli)and staphylococcus aureus(S.aureus).Thereinto,complex 5 displayed best antibacterial effect on E.coli,while complex 9 exhibited effective antibacterial activities against S.aureus.CCDC:2022664,1;2022665,2;2022666,3;2022667,4;2022668,5.