Is the N-of-1 method applicable in bodywork research? Lessons learned using a trial as a methodological pilot

N-of-1 trial designs have rarely been used in bodywork research.Using a recent trial as a methodological pilot,critical issues related to the applicability of N-of-1 trials to bodywork are discussed.These include the issues of carry-over effects,bias-controlling approaches and statistical analysis.The discussion highlights the importance of mixed methods and draws some suggestions for a future research program.N-of-1 trials could be used to provide insights about some essential elements of bodywork modalities and their effectiveness.