中医运动疗法对毒品成瘾者精神行为、体质健康及生命质量干预效果的Meta分析

Meta-analysis of the Intervention Effect of Traditional Chinese Medicine Exercises Therapy on Mental Behavior,Physical Fitness and Quality of Life of Drug Addicts

目的:系统评价中医运动疗法对毒品成瘾患精神行为、体质健康及生命质量的干预效果。方法:通过PubMed、EMbase、PsychINFO、Eric、SportDiscus、Web of Science、中国知网、万方等数据库进行中医运动疗法对毒品依赖患者干预效果的临床随机对照试验(RCT)检索,对纳入文献进行质量评价和偏倚风险评估后,利用RevMan 5.3软件进行Meta分析。结果:共纳入11个RCT,包括1233名毒品成瘾者。Meta分析结果显示,中医运动疗法对毒品成瘾者的抑郁症状改善优于对照组,差异具有统计学意义(SMD=-0.29,95%CI:-0.48,-0.10,P=0.003);中医运动疗法对毒品成瘾者的焦虑症状改善优于对照组,差异具有统计学意义(SMD=-3.14,95%CI:-6.20,-0.07,P=0.04);中医运动疗法对毒品成瘾者的迁延戒断症状改善优于对照组,差异具有统计学意义(SMD=-0.44,95%CI:-0.75,-0.13,P=0.006);中医运动疗法对毒品成瘾者的闭眼单脚站立能力改善优于对照组,差异具有统计学意义(SMD=0.33,95%CI:0.04,0.61,P=0.03);中医运动疗法对毒品成瘾者的渐进性耐力改善优于对照组,差异具有统计学意义(SMD=4.12,95%CI:3.13,5.10,P<0.00001);中医运动疗法对毒品成瘾者的生命质量改善优于对照组,差异具有统计学意义(SMD=0.32,95%CI:0.21,0.42,P<0.00001)。结论:中医运动疗法可以改善毒品成瘾者的情绪状态,提高体质健康水平,提升生命质量,可以在毒品成瘾者中推广和应用。

Objective:To systematically review the efficacy of traditional Chinese medicine exercise therapy on mental behavior,physical fitness and quality of life of drug addicts.Methods:Through PubMed,EMbase,PsychINFO,Eric,SportDiscus,Web of Science,CNKI,Wanfang and other databases to search for clinical randomized controlled trials(RCTs)of the intervention effect of traditional Chinese medicine exercise therapy on drug-dependent patients,and evaluate the quality of the included literature.After assessing the risk of bias,the RevMan 5.3 software was used for Meta-analysis.Results:A total of 11 articles were included,with a total of 1233 addicts.Meta results showed that:The depressive symptoms of drug addicts in the TCM exercise therapy group was better improved than that in the control group,and the difference was statistically significant(SMD=-0.29,95%CI:-0.48,-0.10,P=0.003);the anxiety symptoms of drug addicts in the TCM exercise therapy group was better improved than that in the control group,and the difference was statistically significant(SMD=-3.14,95%CI:-6.20,-0.07,P=0.04);the persistent withdrawal symptoms of drug addicts in the TCM exercise therapy group was better improved than that in the control group,and the difference was statistically significant(SMD=-0.44,95%CI:-0.75,-0.13,P=0.006);the physical fitness of drug addicts standing on one foot with closed eyes in the TCM exercise therapy group was better improved than that in the control group,and the difference was statistically significant(SMD=0.33,95%CI:0.04,0.61,P=0.03);the physical fitness of the progressive endurance test of drug addicts in the TCM exercise therapy group was better improved than that in the control group,and the difference was statistically significant(SMD=4.12,95%CI:3.13,5.10,P<0.00001);the quality of life of drug addicts in the TCM exercise therapy group was better improved than that in the control group,and the difference was statistically significant(SMD=0.32,95%CI:0.21,0.42,P<0.00001).Conclusions:The TCM exercise therapy can improve the mood,physical fitness,and the quality of life of the drug addicts.It can be promoted and applied to drug addicts.