重复经颅磁刺激治疗糖尿病性周围神经病理性疼痛的研究进展

Investigation in the treatment of diabetic peripheral neuropathic pain with repetitive transcranial magnetic stimulation(TMS)

糖尿病性周围神经病理性疼痛是指由糖尿病或糖尿病前期导致的周围神经病理性疼痛,临床上表现为四肢远端对称性的疼痛麻木不适,其中以双下肢受累最为常见,也可表现为单一或单组神经支配区域的疼痛不适如臂丛神经、腰骶神经等,严重影响患者及其家属的正常生活。重复经颅磁刺激是一种安全且副作用小,无创无痛操作方便的治疗糖尿病性周围神经病理性疼痛的方法,减轻患者的疼痛、使之早日恢复正常生活是治疗的首要目标。介绍重复经颅磁刺激治疗糖尿病性周围神经病理性疼痛的机制以及治疗方案、效果、安全性等。

Diabetic peripheral neuropathic pain is caused by diabetes or pre-diabetes peripheral neuropathy pain,clinically characterized by pain numbness of the limbs distal symmetric discomfort,including double lower limbs were affected in the most common,and can also be shown as a single or a single set of innervation area of discomfort such as brachial plexus,lumbosacral nerve pain,seriously affect the normal life of patients and their families.Repetitive transcranial magnetic stimulation(TMS)is a safe,non-invasive,painless and convenient method for the treatment of diabetic peripheral neuropathic pain with few side effects.This paper briefly describes the mechanism,treatment plan,effect and safety of repetitive transcranial magnetic stimulation(TMS)in the treatment of diabetic peripheral neuropathic pain.