血常规联合C反应蛋白、降钙素原检测在儿童传染性单核细胞增多症与化脓性扁桃体炎鉴别诊断中的价值

Value of blood routine combined with C-reactive protein and procalcitonin detection in the differential diagnosis of infectious mononucleosis and suppurative tonsillitis in children

目的分析血常规联合C反应蛋白、降钙素原检测在儿童传染性单核细胞增多症与化脓性扁桃体炎鉴别诊断中的价值。方法选取2014年1月至2019年12月我院收治的59例传染性单核细胞增多症患儿(A组)与59例化脓性扁桃体炎患儿(B组)。所有患儿均行实验室相关指标检测。比较两组的临床表现(发热、咽痛、淋巴结肿大、肝脾肿大、全身不适)、C反应蛋白及降钙素原水平、血常规指标(中性粒细胞、白细胞、血小板计数及血红蛋白水平)。结果两组发热患儿占比比较,差异无统计学意义(P>0.05);A组淋巴结肿大、肝脾肿大患儿占比高于B组,咽痛、全身不适患儿占比低于B组,差异具有统计学意义(P<0.05)。A组C反应蛋白及降钙素原水平低于B组,差异具有统计学意义(P<0.05)。A组中性粒细胞及血小板计数低于B组,白细胞计数及血红蛋白水平高于B组,差异具有统计学意义(P<0.05)。结论血常规联合C反应蛋白、降钙素原检测在儿童传染性单核细胞增多症与化脓性扁桃体炎鉴别诊断中的价值较高。

Objective To analyze the value of blood routine combined with C-reactive protein and procalcitonin detection in the differential diagnosis of infectious mononucleosis and suppurative tonsillitis in children.Methods Fifty-nine children with infectious mononucleosis(group A)and 59 children with suppurative tonsillitis(group B)admitted in our hospital from January 2014 to December 2019 were selected.All children were tested by laboratory related indicators.The clinical manifestations(fever,pharyngeal pain,lymphadenopathy,hepatosplenomegaly,general discomfort),C reactive protein and procalcitonin levels,blood routine indexes(neutrophil,leukocyte,platelet count and hemoglobin level)of the two groups were compared.Results There was no significant difference in the proportion of children with fever between the two groups(P>0.05);the proportion of children with lymphadenopathy and hepatosplenomegaly in the group A were higher than those in the group B,the proportion of children with pharyngeal pain and general discomfort in the group A were lower than those in the group B,and the differences were statistically significant(P<0.05).The levels of C-reactive protein and procalcitonin in the group A were lower than those in the group B,and the differences were statistically significant(P<0.05).The neutrophil and platelet count in the group A were lower than those in the group B,the leukocyte count and hemoglobin level in the group B were higher than those in the group B,and the differences were statistically significant(P<0.05).Conclusion Blood routine combined with C-reactive protein and procalcitonin detection in the differential diagnosis of infectious mononucleosis and suppurative tonsillitis in children has high value.